Rhoeadine
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Preferred IUPAC name
(5bR,13bR,15S)-15-Methoxy-6-methyl-5b,6,7,8,13b,15-hexahydro-2H,11H-[1,3]dioxolo[4,5-h][1,3]dioxolo[4′,5′:7,8][2]benzopyrano[3,4-a][4]benzazepine | |
Other names
Rheadine; Rhoeadin
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3D model (JSmol)
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PubChem CID
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CompTox Dashboard (EPA)
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Properties | |
C21H21NO6 | |
Molar mass | 383.400 g·mol−1 |
Density | 1.45 g/cm3 |
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa). | |
what is ?) | (|
Infobox references | |
Rhoeadine (rheadine) is an alkaloid derived from the flowers of the corn poppy (Papaver rhoeas).[1] It has been studied for its potential use in the treatment of morphine dependence.[2]
Toxicity[]
5 different patients were admitted to ER after being intoxicated with corn poppy. Symptoms of intoxication include nausea, vomiting, confusion, seizures, myosis and arrhythmia.[3]
References[]
- ^ Montgomery, Craig T.; Cassels, Bruce K.; Shamma, Maurice (1983-07-01). "The Rhoeadine Alkaloids". Journal of Natural Products. 46 (4): 441–453. doi:10.1021/np50028a001. ISSN 0163-3864. Retrieved 2021-04-07.
- ^ Shams, J.; Sahraei, H.; Faghih-Monzavi, Z.; Salimi, SH; Fatemi, SM; Pourmatabbed, A.; Ghoshooni, H.; Kamalinejad, M. (2008). "Effects of Papaver rhoeas Extract on the Tolerance Development to Analgesic Effects of Morphine in Mice". Iranian Journal of Pharmaceutical Research. 7 (2). doi:10.22037/ijpr.2010.757.
- ^ Günaydın, Yahya Kemal; Dündar, Zerrin Defne; Çekmen, Bora; Akıllı, Nazire Belgin; Köylü, Ramazan; Cander, Başar (2015-05-13). "Intoxication due to Papaver rhoeas (Corn Poppy): Five Case Reports". Case Reports in Medicine. 2015: –321360. doi:10.1155/2015/321360. ISSN 1687-9627. PMC 4444563. PMID 26074968.
Categories:
- Alkaloids
- Azepanes
- Benzodioxoles
- Heterocyclic compounds with 6 rings