Ronald Duman
 | This article may rely excessively on sources too closely associated with the subject, potentially preventing the article from being verifiable and neutral. (May 2014) |
Ronald Duman | |
|---|---|
| Born | Ronald Stanton Duman February 6, 1954 Ebensburg, Pennsylvania, U.S. |
| Died | February 1, 2020 (aged 65) Guilford, Connecticut, U.S. |
| Alma mater | College of William & Mary University of Texas Health Science Center at Houston |
| Occupation | Neuroscientist |
Ronald Stanton Duman (February 6, 1954 – February 1, 2020)[1] was a Professor of Psychiatry and Pharmacology Director, Division of Molecular Psychiatry and Abraham Ribicoff Research Facilities at Yale University.[2]
Education[]
Duman graduated from the College of William & Mary (where he played varsity football as a middle linebacker) in 1976. He received his Ph.D. from the University of Texas Health Science Center at Houston (UTHealth) in 1985.
Career[]
Ron Duman's research centered around the biological mechanisms behind antidepressants. In his landmark 1995 paper, he discovered that antidepressants increase the gene expression of Brain-Derived Neurotrophic Factor, or (BDNF)[3] in the hippocampus. In a later paper he discovered that the downstream effect of BDNF is to increase neurogenesis or the formation of new neurons in the dentate gyrus of the hippocampus.[4]
The results of this work led him to formulate the hypothesis that depression is caused by a decrease in hippocampal neurogenesis caused by elevated cortisol levels.
Death[]
Ronald Duman died on February 1, 2020 at the age of 65 while hiking in Guilford, Connecticut.[5]
Notes[]
- ^ "Ronald Stanton Duman, PhD (Obituary)". The Tribune-Democrat. February 6, 2020. Retrieved February 8, 2020.
- ^ Duman's Yale Faculty Website Archived 18 December 2010 at WebCite
- ^ First paper demonstrating the link between antidepressants and BDNF levels Archived 18 December 2010 at WebCite
- ^ Abstract of paper demonstrating that antidepressants increase neurogenesis Archived 18 December 2010 at WebCite
- ^ Ronald S. Duman, PhD, Pioneering Neuroscientist of Stress, Depression, and Antidepressant Treatment Dies at 65
- 1954 births
- 2020 deaths
- American neuroscientists
- American psychiatrists
- People from Ebensburg, Pennsylvania
- Scientists from Pennsylvania
- University of Texas Health Science Center at Houston alumni
- William & Mary Tribe football players
- Yale School of Medicine faculty
- American psychiatrist stubs