From Wikipedia, the free encyclopedia
Solute carrier family 25 member 39 is a protein that in humans is encoded by the SLC25A39 gene .[5] [6] The protein has been shown to be necessary for the import of the major antioxidant glutathione into the mitochondria . [7] [8]
See also [ ]
References [ ]
^ a b c GRCh38: Ensembl release 89: ENSG00000013306 - Ensembl , May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000018677 - Ensembl , May 2017
^ "Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ "Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Haitina T, Lindblom J, Renstrom T, Fredriksson R (Nov 2006). "Fourteen novel human members of mitochondrial solute carrier family 25 (SLC25) widely expressed in the central nervous system" . Genomics . 88 (6): 779–90. doi :10.1016/j.ygeno.2006.06.016 . PMID 16949250 .
^ "Entrez Gene: SLC25A39 solute carrier family 25, member 39" .
^ Wang Y, Yen FS, Zhu XG, Timson RC, Weber R, Xing C, Liu Y, Allwein B, Luo H, Yeh H, Heissel S, Unlu G, Gamazon ER, Kharas MG, Hite R, Birsoy K (Nov 2021). "SLC25A39 is necessary for mitochondrial glutathione import in mammalian cells". Nature . 599 (7883): 136–140. doi :10.1038/s41586-021-04025-w . PMID 34707288 .
^ "Scientists discover how mitochondria import antioxidants" . Retrieved January 22, 2022 .
Further reading [ ]
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7. doi :10.1101/gr.2596504 . PMC 528928 . PMID 15489334 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5. doi :10.1038/ng1285 . PMID 14702039 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903. doi :10.1073/pnas.242603899 . PMC 139241 . PMID 12477932 .
Simpson JC, Wellenreuther R, Poustka A, et al. (2001). "Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" . EMBO Rep . 1 (3): 287–92. doi :10.1093/embo-reports/kvd058 . PMC 1083732 . PMID 11256614 .
Wiemann S, Weil B, Wellenreuther R, et al. (2001). "Toward a catalog of human genes and proteins: sequencing and analysis of 500 novel complete protein coding human cDNAs" . Genome Res . 11 (3): 422–35. doi :10.1101/gr.GR1547R . PMC 311072 . PMID 11230166 .
Yu XX, Lewin DA, Zhong A, et al. (2001). "Overexpression of the human 2-oxoglutarate carrier lowers mitochondrial membrane potential in HEK-293 cells: contrast with the unique cold-induced mitochondrial carrier CGI-69" . Biochem. J . 353 (Pt 2): 369–75. doi :10.1042/0264-6021:3530369 . PMC 1221580 . PMID 11139402 .
Lai CH, Chou CY, Ch'ang LY, et al. (2000). "Identification of novel human genes evolutionarily conserved in Caenorhabditis elegans by comparative proteomics" . Genome Res . 10 (5): 703–13. doi :10.1101/gr.10.5.703 . PMC 310876 . PMID 10810093 .
This article incorporates text from the United States National Library of Medicine , which is in the public domain .
By group
SLC1–10
(1):
high affinity glutamate and neutral amino-acid transporter
(2): (3): (4): (5): (6): (7): (8): (9): (10):
SLC10A1
SLC10A2
SLC10A3
SLC10A7
10A1
10A2
10A3
10A7
SLC11–20
(11): (12): (13): (14): (15): (16): (17): (18): (19): (20):
SLC21–30
(21):
Organic anion-transporting polypeptide
SLCO1A2
SLCO1B1
SLCO1B3
SLCO1C1
(22):
organic cation/anion/zwitterion transporter
(23): (24): (25): (26): (27): (28): (29): (30):
zinc efflux
SLC30A1
SLC30A3
SLC30A4
SLC30A7
SLC30A8
SLC31–40
(31): (32): (33): (34): (35): (36): (37): (38): (39):
metal ion transporter
SLC39A1
SLC39A2
SLC39A3
SLC39A4
SLC39A6
SLC39A7
SLC39A8
SLC39A9
SLC39A10
SLC39A12
(40):
SLC41–48
(41): (42): (43): (44): (45): (46): (47): (48):
SLCO1–4
O1A2
O1B1
O1B3
O2B1
O431
O4A1
see also solute carrier disorders
Categories :
Genes on human chromosome 17 Solute carrier family Membrane protein stubs Hidden categories:
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