Signal-regulatory protein

Signal-regulatory protein
Signal-regulatory protein
Identifiers
Symbol	SRP
Membranome	42

A Signal-regulatory protein (SIRP) is one of a family of transmembrane glycoproteins involved in immunological signalling, expressed mainly by myeloid cells.^[1]^[2]

Members include :

Signal-regulatory protein alpha, ligand=CD47^[1]
SIRPB1
SIRPG, ligand=CD47^[1]

References[]

^ ^a ^b ^c van Beek EM, Cochrane F, Barclay AN, van den Berg TK (December 2005). "Signal regulatory proteins in the immune system". Journal of Immunology. 175 (12): 7781–7. doi:10.4049/jimmunol.175.12.7781. PMID 16339510.
^ Barclay AN, Brown MH (June 2006). "The SIRP family of receptors and immune regulation". Nature Reviews. Immunology. 6 (6): 457–64. doi:10.1038/nri1859. PMID 16691243. S2CID 7915923.

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[Beak2005-1] van Beek EM, Cochrane F, Barclay AN, van den Berg TK (December 2005). "Signal regulatory proteins in the immune system". Journal of Immunology. 175 (12): 7781–7. doi:10.4049/jimmunol.175.12.7781. PMID 16339510.

[nih-2] Barclay AN, Brown MH (June 2006). "The SIRP family of receptors and immune regulation". Nature Reviews. Immunology. 6 (6): 457–64. doi:10.1038/nri1859. PMID 16691243. S2CID 7915923.

[1]

[2]