TIMM17A

TIMM17A
Identifiers
Aliases	TIMM17A, TIM17, TIM17A, translocase of inner mitochondrial membrane 17 homolog A (yeast), translocase of inner mitochondrial membrane 17A
External IDs	OMIM: 605057 MGI: 1343131 HomoloGene: 115910 GeneCards: TIMM17A
Gene location (Human)
Chr.	Chromosome 1 (human)
End	201,970,664 bp
Gene location (Mouse)
Chr.	Chromosome 1 (mouse)
End	135,313,778 bp
RNA expression pattern
	Top expressed in
	middle temporal gyrus; ; biceps brachii; ; left ventricle; ; myocardium; ; Brodmann area 23; ; right ventricle; ; vastus lateralis muscle;
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	protein-transporting ATPase activity; protein transmembrane transporter activity;
Cellular component	nucleoplasm; integral component of mitochondrial inner membrane; mitochondrial inner membrane; integral component of membrane; TIM23 mitochondrial import inner membrane translocase complex; mitochondrion; membrane;
Biological process	protein targeting to mitochondrion; protein import into mitochondrial matrix; protein transport; intracellular protein transport; positive regulation of protein processing;
	Sources:Amigo / QuickGO
Orthologs
	10440
	21854
	ENSG00000134375
	ENSMUSG00000062580
	Q99595
	Q9Z0V8
	NM_006335
	NM_011590
	NP_006326
	NP_035720; NP_001347786; NP_001347787
	Wikidata
View/Edit Human	View/Edit Mouse

Mitochondrial import inner membrane translocase subunit Tim17-A is an enzyme that in humans is encoded by the TIMM17A gene.^[5]^[6]^[7]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000134375 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000062580 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Bomer U, Rassow J, Zufall N, Pfanner N, Meijer M, Maarse AC (Dec 1996). "The preprotein translocase of the inner mitochondrial membrane: evolutionary conservation of targeting and assembly of Tim17". J Mol Biol. 262 (4): 389–395. doi:10.1006/jmbi.1996.0522. PMID 8893850.
^ Bauer MF, Gempel K, Reichert AS, Rappold GA, Lichtner P, Gerbitz KD, Neupert W, Brunner M, Hofmann S (Jul 1999). "Genetic and structural characterization of the human mitochondrial inner membrane translocase". J Mol Biol. 289 (1): 69–82. doi:10.1006/jmbi.1999.2751. PMID 10339406.
^ "Entrez Gene: TIMM17A translocase of inner mitochondrial membrane 17 homolog A (yeast)".

Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–1178. Bibcode:2005Natur.437.1173R. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–2127. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–45. doi:10.1038/ng1285. PMID 14702039.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Piesse C, Tymms M, Garrafa E, et al. (2002). "Human aminopeptidase B (rnpep) on chromosome 1q32.2: complementary DNA, genomic structure and expression". Gene. 292 (1–2): 129–140. doi:10.1016/S0378-1119(02)00650-9. PMID 12119107.
Moro F, Sirrenberg C, Schneider HC, et al. (1999). "The TIM17.23 preprotein translocase of mitochondria: composition and function in protein transport into the matrix". EMBO J. 18 (13): 3667–3675. doi:10.1093/emboj/18.13.3667. PMC 1171444. PMID 10393182.

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