TRIP10

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TRIP10
Protein TRIP10 PDB 2ct4.png
Available structures
PDBOrtholog search: PDBe RCSB
Identifiers
AliasesTRIP10, CIP4, HSTP, STOT, STP, TRIP-10, thyroid hormone receptor interactor 10
External IDsOMIM: 604504 MGI: 2146901 HomoloGene: 99728 GeneCards: TRIP10
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001288962
NM_001288963
NM_004240

NM_001242389
NM_001242390
NM_001242391
NM_134125

RefSeq (protein)

NP_001275891
NP_001275892
NP_004231

NP_001229318
NP_001229319
NP_001229320
NP_598886

Location (UCSC)Chr 19: 6.74 – 6.75 MbChr 17: 57.25 – 57.26 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Cdc42-interacting protein 4 is a protein that in humans is encoded by the TRIP10 gene.[5][6][7][8]

Interactions[]

TRIP10 has been shown to interact with STAT3,[9] Wiskott-Aldrich syndrome protein,[10] Huntingtin,[11] CDC42,[6][10] AKAP9[12] and RHOQ.[13]

References[]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000125733 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000019487 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Lee JW, Choi HS, Gyuris J, Brent R, Moore DD (July 1995). "Two classes of proteins dependent on either the presence or absence of thyroid hormone for interaction with the thyroid hormone receptor". Mol Endocrinol. 9 (2): 243–54. doi:10.1210/me.9.2.243. PMID 7776974.
  6. ^ a b Aspenstrom P (August 1997). "A Cdc42 target protein with homology to the non-kinase domain of FER has a potential role in regulating the actin cytoskeleton". Curr Biol. 7 (7): 479–87. doi:10.1016/S0960-9822(06)00219-3. PMID 9210375. S2CID 14268690.
  7. ^ Tsuji E, Tsuji Y (April 2001). "Molecular cloning and chromosomal localization of human salt-tolerant protein". Genetica. 108 (3): 259–62. doi:10.1023/A:1004132919896. PMID 11294612. S2CID 22725257.
  8. ^ "Entrez Gene: TRIP10 thyroid hormone receptor interactor 10".
  9. ^ Chung, Young-Hwa; Cho Nam-hyuk; Garcia Maria Ines; Lee Sun-Hwa; Feng Pinghui; Jung Jae U (June 2004). "Activation of Stat3 transcription factor by Herpesvirus saimiri STP-A oncoprotein". J. Virol. United States. 78 (12): 6489–97. doi:10.1128/JVI.78.12.6489-6497.2004. ISSN 0022-538X. PMC 416526. PMID 15163742.
  10. ^ a b Tian, L; Nelson D L; Stewart D M (March 2000). "Cdc42-interacting protein 4 mediates binding of the Wiskott-Aldrich syndrome protein to microtubules". J. Biol. Chem. UNITED STATES. 275 (11): 7854–61. doi:10.1074/jbc.275.11.7854. ISSN 0021-9258. PMID 10713100.
  11. ^ Holbert, Sébastien; Dedeoglu Alpaslan; Humbert Sandrine; Saudou Frédéric; Ferrante Robert J; Néri Christian (March 2003). "Cdc42-interacting protein 4 binds to huntingtin: neuropathologic and biological evidence for a role in Huntington's disease". Proc. Natl. Acad. Sci. U.S.A. United States. 100 (5): 2712–7. Bibcode:2003PNAS..100.2712H. doi:10.1073/pnas.0437967100. ISSN 0027-8424. PMC 151406. PMID 12604778.
  12. ^ Larocca, M Cecilia; Shanks Ryan A; Tian Lan; Nelson David L; Stewart Donn M; Goldenring James R (June 2004). "AKAP350 interaction with cdc42 interacting protein 4 at the Golgi apparatus". Mol. Biol. Cell. United States. 15 (6): 2771–81. doi:10.1091/mbc.E03-10-0757. ISSN 1059-1524. PMC 420101. PMID 15047863.
  13. ^ Chang, Louise; Adams Rachael D; Saltiel Alan R (October 2002). "The TC10-interacting protein CIP4/2 is required for insulin-stimulated Glut4 translocation in 3T3L1 adipocytes". Proc. Natl. Acad. Sci. U.S.A. United States. 99 (20): 12835–40. Bibcode:2002PNAS...9912835C. doi:10.1073/pnas.202495599. ISSN 0027-8424. PMC 130546. PMID 12242347.

Further reading[]

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