TXNL4B

TXNL4B
Available structures
PDB	Ortholog search: PDBe RCSB
List of PDB id codes
	1XBS, 3GIX, 4IN0
Identifiers
Aliases	TXNL4B, DLP, Dim2, thioredoxin like 4B
External IDs	OMIM: 617722 MGI: 2443724 HomoloGene: 9880 GeneCards: TXNL4B
Gene location (Human)
Chr.	Chromosome 16 (human)
End	72,094,431 bp
Gene location (Mouse)
Chr.	Chromosome 8 (mouse)
End	110,300,683 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; internal globus pallidus; ; ovary; ; Right lobe of liver; ; pleura; ; corpus callosum; ; blood; ; testicle; ; stomach;
	More reference expression data
	More reference expression data
Gene ontology
Molecular function	GO:0001948 protein binding;
Cellular component	U5 snRNP; nucleus; nucleoplasm; cytosol; spliceosomal complex; U4/U6 x U5 tri-snRNP complex;
Biological process	mRNA splicing, via spliceosome; cell cycle; mRNA processing; spliceosomal complex assembly; RNA splicing;
	Sources:Amigo / QuickGO
Orthologs
	54957
	234723
	ENSG00000140830
	ENSMUSG00000031723
	Q9NX01
	Q8BUH1
	NM_017853; NM_001142317; NM_001142318; NM_001324354; NM_001324355
	NM_175646
	NP_001135789; NP_001135790; NP_001311283; NP_001311284; NP_060323
	NP_783577
	Wikidata
View/Edit Human	View/Edit Mouse

Thioredoxin-like protein 4B is a protein that in humans is encoded by the TXNL4B gene.^[5]^[6]

Interactions[]

TXNL4B has been shown to interact with PRPF6.^[5]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000140830 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000031723 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ ^a ^b Sun X, Zhang H, Wang D, Ma D, Shen Y, Shang Y (Jul 2004). "DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression". J Biol Chem. 279 (31): 32839–47. doi:10.1074/jbc.M402522200. PMID 15161931.
^ "Entrez Gene: TXNL4B thioredoxin-like 4B".

Further reading[]

Maruyama K, Sugano S (1994). "Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides". Gene. 138 (1–2): 171–4. doi:10.1016/0378-1119(94)90802-8. PMID 8125298.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56. doi:10.1016/S0378-1119(97)00411-3. PMID 9373149.
Zhang YZ, Gould KL, Dunbrack RL JR, Cheng H, Roder H, Golemis EA (2001). "The evolutionarily conserved Dim1 protein defines a novel branch of the thioredoxin fold superfamily" (PDF). Physiol. Genomics. 1 (3): 109–18. doi:10.1152/physiolgenomics.1999.1.3.109. PMID 11015569.
Schelling P, Claus MT, Johner R, Marquez VE, Schulz GE, Scapozza L (2004). "Biochemical and structural characterization of (South)-methanocarbathymidine that specifically inhibits growth of herpes simplex virus type 1 thymidine kinase-transduced osteosarcoma cells". J. Biol. Chem. 279 (31): 32832–8. doi:10.1074/jbc.M313343200. PMID 15163659.
Simeoni F, Arvai A, Bello P, Gondeau C, Hopfner KP, Neyroz P, Heitz F, Tainer J, Divita G (2005). "Biochemical characterization and crystal structure of a Dim1 family associated protein: Dim2". Biochemistry. 44 (36): 11997–2008. doi:10.1021/bi050427o. PMID 16142897.
Jin T, Howard AJ, Golemis EA, Wang Y, Zhang YZ (2006). "Overproduction, purification, crystallization and preliminary X-ray diffraction studies of the human spliceosomal protein TXNL4B". Acta Crystallographica Section F. 61 (Pt 3): 282–4. doi:10.1107/S1744309105002861. PMC 1952293. PMID 16511018.

This article on a gene on human chromosome 16 is a stub. You can help Wikipedia by .

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000140830 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000031723 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid15161931-5] Sun X, Zhang H, Wang D, Ma D, Shen Y, Shang Y (Jul 2004). "DLP, a novel Dim1 family protein implicated in pre-mRNA splicing and cell cycle progression". J Biol Chem. 279 (31): 32839–47. doi:10.1074/jbc.M402522200. PMID 15161931.

[entrez-6] "Entrez Gene: TXNL4B thioredoxin-like 4B".

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