Terpinen-4-ol

Terpinen-4-ol
Names
	Preferred IUPAC name 4-Methyl-1-(propan-2-yl)cyclohex-3-en-1-ol
Identifiers
CAS Number	562-74-3 ;
3D model (JSmol)	Interactive image;
ChEMBL	ChEMBL507795 ;
ChemSpider	10756 ;
ECHA InfoCard	100.008.396
MeSH	terpinenol-4
PubChem CID	11230;
UNII	L65MV77ZG6 ;
CompTox Dashboard (EPA)	DTXSID4044824 ;
	show InChI
	show SMILES
Properties
Chemical formula	C10H18O
Molar mass	154.253 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	(what is ?)
	Infobox references

Terpinen-4-ol is an isomer of terpineol with the chemical formula C₁₀H₁₈O. A primary constituent of tea tree oil,^[1] it is obtained as an extract from the leaves, branches, and bark of Melaleuca alternifolia Cheel.^[2]^[3]^[4] Despite considerable basic and preliminary clinical research of terpinen-4-ol and tea tree oil, its biological properties and potential for clinical uses have not been established as of 2019.^[2] It may be a factor in the contact dermatitis of tea tree oil when used topically.^[2]^[3]

Terpinen-4-ol occurs in Juniperus communis and is thought to be the reason why this wood is highly resistant to rot.^{[citation needed]}

Additional images[]

Synthesis

References[]

^ "Tea tree oil". Drugs and Lactation Database (LactMed), National Library of Medicine, US National Institutes of Health. 3 December 2018. Retrieved 31 July 2019.
^ Jump up to: ^a ^b ^c "Tea tree oil". Drugs.com. 17 June 2019. Retrieved 31 July 2019.
^ Jump up to: ^a ^b de Groot, Anton C.; Schmidt, Erich (13 May 2016). "Tea tree oil: contact allergy and chemical composition". Contact Dermatitis. 75 (3): 129–143. doi:10.1111/cod.12591. ISSN 0105-1873.
^ Hammer, K. A.; Carson, C. F.; Riley, T. V. (2012). "Effects of Melaleuca alternifolia (Tea Tree) Essential Oil and the Major Monoterpene Component Terpinen-4-ol on the Development of Single- and Multistep Antibiotic Resistance and Antimicrobial Susceptibility". Antimicrobial Agents and Chemotherapy. 56 (2): 909–915. doi:10.1128/AAC.05741-11. PMC 3264233. PMID 22083482.CS1 maint: multiple names: authors list (link)

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[lact-1] "Tea tree oil". Drugs and Lactation Database (LactMed), National Library of Medicine, US National Institutes of Health. 3 December 2018. Retrieved 31 July 2019.

[drugs-2] Jump up to: ^a ^b ^c "Tea tree oil". Drugs.com. 17 June 2019. Retrieved 31 July 2019.

[Groot-3] Jump up to: ^a ^b de Groot, Anton C.; Schmidt, Erich (13 May 2016). "Tea tree oil: contact allergy and chemical composition". Contact Dermatitis. 75 (3): 129–143. doi:10.1111/cod.12591. ISSN 0105-1873.

[4] Hammer, K. A.; Carson, C. F.; Riley, T. V. (2012). "Effects of Melaleuca alternifolia (Tea Tree) Essential Oil and the Major Monoterpene Component Terpinen-4-ol on the Development of Single- and Multistep Antibiotic Resistance and Antimicrobial Susceptibility". Antimicrobial Agents and Chemotherapy. 56 (2): 909–915. doi:10.1128/AAC.05741-11. PMC 3264233. PMID 22083482.CS1 maint: multiple names: authors list (link)

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