Tiflorex
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Formula | C12H16F3NS |
Molar mass | 263.32 g·mol−1 |
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Chirality | Racemic mixture |
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Tiflorex, formerly known as flutiorex, is a stimulant amphetamine. Its most pronounced effect is in suppression of appetite; it has little effect on pulse rate, sleep, or mood.[1] It was found to be twice as potent an anorectic as fenfluramine.[2]
SL 72.340-d was cited to be 4x the anorectant potency of fenfluramine (ED50=1.4 mg/kg vs 5.6 mg/kg).[3]
References[]
- ^ Silverstone T, Fincham J, Plumley J (April 1979). "An evaluation of the anorectic activity in man of a sustained release formulation of tiflorex". British Journal of Clinical Pharmacology. 7 (4): 353–6. doi:10.1111/j.1365-2125.1979.tb00945.x. PMC 1429648. PMID 444355.
- ^ Giudicelli JF, Richer C, Berdeaux A (February 1976). "Preliminary assessment of flutiorex, a new anorectic drug, in man". British Journal of Clinical Pharmacology. 3 (1): 113–21. doi:10.1111/j.1365-2125.1976.tb00578.x. PMC 1428817. PMID 788737.
- ^ Stuart S (2013-09-11). Abstracts: Sixth International Congress of Pharmacology. ISBN 9781483152530.
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ATC code: N06B |
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See also: Receptor/signaling modulators • Monoamine reuptake inhibitors • Adrenergics • Dopaminergics • Serotonergics • Monoamine metabolism modulators • Monoamine neurotoxins |
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