Tomislav Friščić

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Tomislav Friščić
Alma materUniversity of Zagreb

University of Iowa

University of Cambridge
Scientific career
FieldsChemistry
InstitutionsMcGill University (2011-present)
Academic advisorsBranko Kaitner
Leonard MacGillivray
Websitefriscic.research.mcgill.ca

Tomislav Friščić is a Professor of chemistry at McGill University, Montréal and a Tier-1 Canada Research Chair in mechanochemistry and solid-state chemistry. His research focus is at the interface of Green Chemistry and Materials Science, developing solvent-free chemistry and mechanochemistry for the cleaner, efficient synthesis of molecules and materials, including organic solids such as pharmaceutical cocrystals, coordination polymers and Metal-Organic Frameworks (MOFs), and a wide range of organic targets such as active pharmaceutical ingredients.[1] He is a Fellow of the Royal Society of Chemistry (RSC) and a member of the College of New Scholars, Artists and Scientists of the Royal Society of Canada. He has served on the Editorial Board of CrystEngComm, the Early Career Board of the ACS journal ACS Sustainable Chemistry & Engineering, and was as an Associate Editor for the journal Molecular Crystals & Liquid Crystals. He was a Topic Editor, and is currently the Social Media Editor and member of the Editorial Advisory Board of the journal Crystal Growth & Design published by the American Chemical Society (ACS). He famously has a dog named Zizi.

Education[]

Friščić was born in 1978, and received his B.Sc. in 2001 from the University of Zagreb with Prof. Branko Kaitner. He then moved to obtain a Ph.D. with Prof. Leonard R. MacGillivray at the University of Iowa until 2006.[2] He was a post-doctoral research associate with Prof. William Jones at the Pfizer Institute for Pharmaceutical Materials Science and University of Cambridge (2006-2008), and then a Herchel Smith Research Fellow and a Fellow of Sidney Sussex College at the University of Cambridge (2008-2011).

Career and research[]

Friščić started his tenure track in 2011 at the Chemistry Department of McGill University as an Assistant Professor, received tenure and was promoted to Associate Professor in early 2016, and has been a full Professor and William Dawson Scholar since November 2019. His group's research focuses on using solvent-free Green Chemistry, including mechanochemistry, accelerated aging, reactive aging (RAging) and other related techniques like acoustic mixing[3] for various applications,[4][5] [6] such as noble metal recycling[7][8][9] or cellulose enzymatic depolymerization.[10][11] With his former student Dr. Cristina Mottillo he founded in 2016 a startup called ACSYNAM,[12] that makes hypergolic MOFs for rocket and space propulsion.[13] [14][15]

Selected publications[]

Metal recycling

  • Oxidative Mechanochemistry: Direct, Room‐Temperature, Solvent‐Free Conversion of Palladium and Gold Metals into Soluble Salts and Coordination Complexes[16]

Acoustic mixing

  • Simple, scalable mechanosynthesis of metal–organic frameworks using liquid-assisted resonant acoustic mixing[17]

Solid-state enzymatic depolymerisation of cellulose

  • Solvent‐Free Enzyme Activity: Quick, High‐Yielding Mechanoenzymatic Hydrolysis of Cellulose into Glucose[18]

Hypergolic MOFs for rocket fuel applications

  • Hypergolic Triggers as Co‐crystal Formers: Co‐crystallization for Creating New Hypergolic Materials with Tunable Energy Content[19]
  • Hypergolic zeolitic imidazolate frameworks (ZIFs) as next-generation solid fuels: Unlocking the latent energetic behavior of ZIFs[20]

References[]

  1. ^ "Prof. Friščić". friscic.research.mcgill.ca. Retrieved 2020-04-20.
  2. ^ "Tomislav Friščić". Angewandte Chemie International Edition. 59 (1): 30. 2020-01-02. doi:10.1002/anie.201908053. ISSN 1433-7851. PMID 31856392.
  3. ^ Hay2020-04-01T13:36:00+01:00, Geraldine. "Mechanochemistry drops the ball in MOF synthesis". Chemistry World. Retrieved 2020-04-20.
  4. ^ "Le chercheur qui voulait réinventer la chimie". La Presse (in French). 2017-04-03. Retrieved 2020-04-20.
  5. ^ Lim, Xiaozhi (2016-07-18). "Grinding Chemicals Together in an Effort to be Greener". The New York Times. ISSN 0362-4331. Retrieved 2020-04-20.
  6. ^ Lemonick, Sam. "Let's Be Realistic About Mechanochemistry". Forbes. Retrieved 2020-04-20.
  7. ^ Mark Peplow, special to C&EN. "Shaking up gold and palladium | January 29, 2018 Issue - Vol. 96 Issue 5 | Chemical & Engineering News". cen.acs.org. Retrieved 2020-04-20.
  8. ^ "Greener way to refine metals needs a good shake". Futurity. 2017-06-08. Retrieved 2020-04-20.
  9. ^ "A more sustainable way to refine metals: New method could reduce environmental impact of extracting metals from raw materials and post-consumer electronics". ScienceDaily. Retrieved 2020-04-20.
  10. ^ "Chemists get physical and RAge against bulk solvents". The Chemical Institute of Canada. 2018-05-01. Retrieved 2020-04-20.
  11. ^ January, Derek Lowe 29; 2018 (2018-01-29). "Down At the Small Surfaces". In the Pipeline. Retrieved 2020-04-20.CS1 maint: numeric names: authors list (link)
  12. ^ "ACSYNAM - | Next-generation propellants". ACSYNAM. Retrieved 2020-04-20.
  13. ^ Katherine.gombaymcgill.ca, Contact Information Contact: Katherine Gombay Organization: Media Relations Office Email. "Rocket fuel that's cleaner, safer and still full of energy". Newsroom. Retrieved 2020-04-20.
  14. ^ "Podcast: When rocket chemistry blasted off and came back to Earth". Chemical & Engineering News. Retrieved 2020-04-20.
  15. ^ Dunphy, Siobhán (2019-04-08). "Greener space travel? Scientists unlock the door to cleaner rocket fuel". European Scientist. Retrieved 2020-04-20.
  16. ^ Do, Jean-Louis; Tan, Davin; Friščić, Tomislav (2018-03-01). "Oxidative Mechanochemistry: Direct, Room-Temperature, Solvent-Free Conversion of Palladium and Gold Metals into Soluble Salts and Coordination Complexes". Angewandte Chemie International Edition. 57 (10): 2667–2671. doi:10.1002/anie.201712602. PMID 29345752.
  17. ^ Titi, Hatem M.; Do, Jean-Louis; Howarth, Ashlee J.; Nagapudi, Karthik; Friščić, Tomislav (2020). "Simple, scalable mechanosynthesis of metal–organic frameworks using liquid-assisted resonant acoustic mixing (LA-RAM)". Chemical Science. 11 (29): 7578–7584. doi:10.1039/D0SC00333F. ISSN 2041-6520.
  18. ^ Hammerer, Fabien; Loots, Leigh; Do, Jean-Louis; Therien, J. P. Daniel; Nickels, Christopher W.; Friščić, Tomislav; Auclair, Karine (2018-03-01). "Solvent-Free Enzyme Activity: Quick, High-Yielding Mechanoenzymatic Hydrolysis of Cellulose into Glucose". Angewandte Chemie International Edition. 57 (10): 2621–2624. doi:10.1002/anie.201711643. PMID 29342316.
  19. ^ Titi, Hatem M.; Arhangelskis, Mihails; Rachiero, Giovanni P.; Friščić, Tomislav; Rogers, Robin D. (2019-12-16). "Hypergolic Triggers as Co‐crystal Formers: Co‐crystallization for Creating New Hypergolic Materials with Tunable Energy Content". Angewandte Chemie International Edition. 58 (51): 18399–18404. doi:10.1002/anie.201908690. ISSN 1433-7851. PMID 31609511.
  20. ^ Titi, H. M.; Marrett, J. M.; Dayaker, G.; Arhangelskis, M.; Mottillo, C.; Morris, A. J.; Rachiero, G. P.; Friščić, T.; Rogers, R. D. (April 2019). "Hypergolic zeolitic imidazolate frameworks (ZIFs) as next-generation solid fuels: Unlocking the latent energetic behavior of ZIFs". Science Advances. 5 (4): eaav9044. Bibcode:2019SciA....5.9044T. doi:10.1126/sciadv.aav9044. ISSN 2375-2548. PMC 6450693. PMID 30972369.
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