Trypanotolerance

From Wikipedia, the free encyclopedia

A trypanotolerant organism is one which is relatively less affected by trypanosome infestation.

By host[]

In humans[]

In livestock[]

Some breeds are known for their trypanotolerance. This is especially important in Africa where a few particular trypanosomes are major economic and agricultural pests.[1][2][3][4]

Trypanotolerant livestock breeds[]

History of genetic research[]

Trypanotolerance had previously been achieved through normal livestock breeding in cattle, but genetic analysis was becoming a serious option in the 1980s. The effort that would eventually bear fruit began with a conversation between Peter Brumby - then at the International Livestock Centre for Africa - and Morris Soller in 1985. This was followed by the opening of the shortlived International Trypanotolerance Center in the Gambia in 1987 with a seminar on the genome mapping project that would continue beyond the Center itself. The project was then actually completed by the ILRI - the successor to the ILCA - in 2003.[7]

References[]

  1. ^ D'IETEREN, G.D.M.; AUTHIE, E.; WISSOCQ, N.; MURRAY, M. (1998-04-01). "Trypanotolerance, an option for sustainable livestock production in areas at risk from trypanosomosis". Revue Scientifique et Technique de l'OIE. O.I.E (World Organisation for Animal Health). 17 (1): 154–175. doi:10.20506/rst.17.1.1088. ISSN 0253-1933. PMID 9638808.
  2. ^ a b Kim, Soo-Jin; Ka, Sojeong; Ha, Jung-Woo; Kim, Jaemin; Yoo, DongAhn; Kim, Kwondo; Lee, Hak-Kyo; Lim, Dajeong; Cho, Seoae; Hanotte, Olivier; Mwai, Okeyo Ally; Dessie, Tadelle; Kemp, Stephen; Oh, Sung Jong; Kim, Heebal (2017-05-12). "Cattle genome-wide analysis reveals genetic signatures in trypanotolerant N'Dama". BMC Genomics. BioMed Central/Springer Science and Business Media LLC. 18 (1). doi:10.1186/s12864-017-3742-2. ISSN 1471-2164.
  3. ^ "Trypanotolerant livestock in the context of trypanosomiasis intervention strategies". Food and Agriculture Organization of the United Nations. Retrieved 2021-02-20.
  4. ^ "Trypanotolerance in West African cattle". CIRAD (Centre de coopération internationale en recherche agronomique pour le développement). Retrieved 2021-02-20.
  5. ^ R. T. Wilson (1991). Small Ruminant Production and the Small Ruminant Genetic Resource in Tropical Africa Rome: Food and Agriculture Organization of the United Nations. ISBN 9789251029985.
  6. ^ "HAUT DEGRE DE TOLERANCE A LA TRYPANOSOMOSE DES MOUTONS ET DES CHEVRES DE RACE NAINE DJALLONKE DES REGIONS SUD-GUINEENNES DU TOGO : COMPARAISON AVEC DES BOVINS TRYPANOTOLERANTS". . 1987. doi:10.19182/REMVT.8696. PMID 3444966. S2CID 86116225.
  7. ^ Soller, Morris (2015-02-16). "If a Bull Were a Cow, How Much Milk Would He Give?". Annual Review of Animal Biosciences. Annual Reviews. 3 (1): 1–17. doi:10.1146/annurev-animal-022114-110751. ISSN 2165-8102.
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