Ulrich K. Laemmli
Ulrich K. Laemmli | |
|---|---|
| Nationality | Switzerland |
| Known for | SDS-PAGE |
| Awards | Louis-Jeantet Prize for Medicine (1996) Marcel Benoist Prize (1988) |
| Scientific career | |
| Fields | Biochemistry |
Ulrich K. Laemmli is a Professor in the biochemistry and molecular biology departments at University of Geneva. He is known for the refinement of SDS-PAGE, a widely used method for separating proteins based on their electrophoretic mobility.[1] His paper describing the method is among the most cited scholarly journal articles of all time.[2][3][4] His current research involves studying the structural organization of nuclei and chromatin within the cell.[5]
Major scientific contributions[]
Although electrophoresis was used to separate proteins before Laemmli's work, he made significant improvements to the method. The term "Laemmli buffer" is often used to describe an SDS-containing buffer that is used to prepare (denature) samples for SDS-PAGE.[1][6]
Awards and honors[]
- Louis-Jeantet Prize for Medicine – 1996[7]
- Elected fellow of the American Association for the Advancement of Science – 2006[8][9]
References[]
- ^ Jump up to: a b Laemmli UK (August 1970). "Cleavage of structural proteins during the assembly of the head of bacteriophage T4". Nature. 227 (5259): 680–685. doi:10.1038/227680a0. PMID 5432063.
- ^ "Bio Infobank Library-Kinetics". BioInfoBank Institute. Retrieved 9 January 2010.
- ^ Garfield, Eugene (1998). "THE USE OF JOURNAL IMPACT FACTORS AND CITATION ANALYSIS FOR EVALUATION OF SCIENCE". The Scientist. Retrieved 9 January 2010.
- ^ Garfield, Eugene (12 February 1990). "The most cited papers of all time" (PDF). Current Comments. 13 (7): 2–14. Retrieved 9 January 2010.
- ^ "PROFESSOR ULRICH K. LAEMMLI". Geneva, Switzerland: Département de biologie moléculaire - Université de Genève. 17 October 2008. Retrieved 7 January 2010.
- ^ "SDS-Polyacrylamide Gel Electrophoresis (SDS-PAGE)". Gainesville, FL: EnCor Biotechnology Inc. 2010. Retrieved 9 January 2010.
- ^ "The winners of the Louis-Jeantet Prize for medicine". Louis-Jeante Foundation. Retrieved 14 October 2009.
- ^ LEMPINEN, EDWARD W. (24 November 2006). "AAAS Members Elected as Fellows" (PDF). Science. AAAS. 314 (5803): 1256–60 [1258]. doi:10.1126/science.314.5803.1256. Retrieved 7 January 2009.
- ^ "2006 annual report" (PDF). AAAS. 2006. p. 22. Retrieved 7 January 2010.
External links[]
 | This article about a Swiss scientist is a stub. You can help Wikipedia by . |
- Living people
- Swiss biochemists
- University of Geneva faculty
- Fellows of the American Association for the Advancement of Science
- Swiss scientist stubs