WASF3

From Wikipedia, the free encyclopedia
WASF3
Identifiers
AliasesWASF3, Brush-1, SCAR3, WAVE3, WAS protein family member 3, WASP family member 3
External IDsOMIM: 605068 MGI: 2658986 HomoloGene: 68527 GeneCards: WASF3
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_001291965
NM_006646

NM_145155

RefSeq (protein)

NP_001278894
NP_006637
NP_006637.2

NP_660137

Location (UCSC)Chr 13: 26.56 – 26.69 MbChr 5: 146.32 – 146.41 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Wiskott-Aldrich syndrome protein family member 3 is a protein that in humans is encoded by the WASF3 gene.[5][6]

This gene encodes a member of the Wiskott-Aldrich syndrome protein family. The gene product is a protein that forms a multiprotein complex that links receptor kinases and actin. Binding to actin occurs through a C-terminal verprolin homology domain in all family members. The multiprotein complex serves to tranduce signals that involve changes in cell shape, motility or function.[6]

References[]

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000132970 - Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000029636 - Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Suetsugu S, Miki H, Takenawa T (Jul 1999). "Identification of two human WAVE/SCAR homologues as general actin regulatory molecules which associate with the Arp2/3 complex". Biochem Biophys Res Commun. 260 (1): 296–302. doi:10.1006/bbrc.1999.0894. PMID 10381382.
  6. ^ a b "Entrez Gene: WASF3 WAS protein family, member 3".

Further reading[]

Retrieved from ""