WASHC2C

WASHC2C
Identifiers
Aliases	WASHC2C, FAM21A, VPEF, FAM21C, family with sequence similarity 21 member C, WASH complex subunit 2C
External IDs	OMIM: 613631 MGI: 106463 HomoloGene: 41686 GeneCards: WASHC2C
Gene location (Human)
Chr.	Chromosome 10 (human)
End	45,792,961 bp
Gene location (Mouse)
Chr.	Chromosome 6 (mouse)
End	116,239,647 bp
RNA expression pattern
	Top expressed in
	sural nerve; ; Achilles tendon; ; testicle; ; cerebellar hemisphere; ; Body of pancreas;
	More reference expression data
	n/a
Gene ontology
Molecular function	phosphatidylinositol-3-phosphate binding; phosphatidylinositol-3,5-bisphosphate binding; phosphatidylinositol-3,4-bisphosphate binding; phosphatidylinositol-4-phosphate binding; phosphatidylinositol-5-phosphate binding; GO:0001948 protein binding; phosphatidylinositol-4,5-bisphosphate binding; phosphatidylinositol-3,4,5-trisphosphate binding; lipid binding; retromer complex binding;
Cellular component	early endosome membrane; intracellular membrane-bounded organelle; membrane; plasma membrane; retromer complex; early endosome; nucleolus; endosome; WASH complex; cytosol;
Biological process	negative regulation of barbed-end actin filament capping; retrograde transport, endosome to Golgi; protein transport; regulation of substrate adhesion-dependent cell spreading; protein localization to endosome;
	Sources:Amigo / QuickGO
Orthologs
	253725
	28006
	ENSG00000172661
	ENSMUSG00000024104
	Q9Y4E1
	Q6PGL7
	NM_001169106; NM_001169107; NM_015262; NM_001330074
	NM_026585
NP_001162577; NP_001162578; NP_001317003; NP_056077; NP_001354322;
	NP_001354323; NP_001354324; NP_001354325; NP_001354326; NP_001354327; NP_001354328; NP_001354329; NP_001354330; NP_001354331; NP_001354332; NP_001354333; NP_001354334; NP_001354335; NP_001354336; NP_001354337; NP_001354338; NP_001354339; NP_001354340; NP_001354341; NP_001354342; NP_001354343; NP_001354344; NP_001354345
	NP_080861
	Wikidata
View/Edit Human	View/Edit Mouse

WASH complex subunit 2C is a protein that in humans is encoded by the WASHC2C gene.^[5]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000172661 - Ensembl, May 2017
^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000024104 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: FAM21C family with sequence similarity 21, member C".

Further reading[]

Nagase T, Ishikawa K, Miyajima N, et al. (1998). "Prediction of the coding sequences of unidentified human genes. IX. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (1): 31–9. doi:10.1093/dnares/5.1.31. PMID 9628581.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ota T, Suzuki Y, Nishikawa T, et al. (2004). "Complete sequencing and characterization of 21,243 full-length human cDNAs". Nat. Genet. 36 (1): 40–5. doi:10.1038/ng1285. PMID 14702039.
Brill LM, Salomon AR, Ficarro SB, et al. (2004). "Robust phosphoproteomic profiling of tyrosine phosphorylation sites from human T cells using immobilized metal affinity chromatography and tandem mass spectrometry". Anal. Chem. 76 (10): 2763–72. doi:10.1021/ac035352d. PMID 15144186.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. doi:10.1038/nature02462. PMID 15164054.
Beausoleil SA, Jedrychowski M, Schwartz D, et al. (2004). "Large-scale characterization of HeLa cell nuclear phosphoproteins". Proc. Natl. Acad. Sci. U.S.A. 101 (33): 12130–5. doi:10.1073/pnas.0404720101. PMC 514446. PMID 15302935.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569. S2CID 13709685.
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol. 24 (10): 1285–92. doi:10.1038/nbt1240. PMID 16964243. S2CID 14294292.
Olsen JV, Blagoev B, Gnad F, et al. (2006). "Global, in vivo, and site-specific phosphorylation dynamics in signaling networks". Cell. 127 (3): 635–48. doi:10.1016/j.cell.2006.09.026. PMID 17081983. S2CID 7827573.

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[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000172661 - Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024104 - Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: FAM21C family with sequence similarity 21, member C".

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