Wolfgang Baumeister

From Wikipedia, the free encyclopedia

Wolfgang Baumeister (born November 22, 1946 in Wesseling bordering Cologne) is a German molecular biologist and biophysicist. His research has been pivotal in the development of Cryoelectron tomography.

Education and career[]

After completing his Abitur, Wolfgang Baumeister studied biology, chemistry, and physics from 1966 to 1967 at the University of Münster and from 1967 to 1969 at the University of Bonn. At the Heinrich Heine University Düsseldorf he was a graduate student from 1970 to 1973 and a research associate from 1973 to 1980 in the department of biophysics. He received his Promotion in 1973 and his Habilitation in 1978. From 1981 to 1982 he was a Heisenberg Fellow at the physics department of the Cavendish Laboratory of England's University of Cambridge.[1]

From 1983 to 1987 he was group leader (with rank C3, Professor Extraordinarius) of the “Molecular Structural Biology” working group at the Max Planck Institute (MPI) of Biochemistry in Martinsried near Munich.[1] The MPI's research department of “Molecular Structural Biology” does research involving molecular biological structures revealed by electron microscopy, cryo-electron tomography, protein and cell structure, and protein degradation[2] He was an außerplanmäßiger Professor from 1984 to 1987 at the University of Düsseldorf and is since 1987 an außerplanmäßiger Professor in the Faculty of Chemistry of the Technical University of Munich. Since 1988 he is the head of the Max Planck Institute of Biochemistry's department of structural biology.[1] Since 2000 he has also been an honorary professor in the Faculty of Physics of the Technical University of Munich.[3]

Baumeister has served on the editorial boards of several journals, including Current Biology, the Journal of Microscopy, the Journal of Structural Biology, and Trends in Cell Biology.[1] He is now the editor-in-chief of Biochemical and Biophysical Research Communications.[4] He was elected a member of the Bavarian Academy of Sciences in 2000,[5] of the German National Academy of Sciences Leopoldina in 2001,[6] and the National Academy of Sciences in 2010. In 2003 he was elected a fellow of the American Academy of Arts and Sciences.[1] He has won many prizes, including in 1998 the Otto Warburg Medal, in 2003 both the Louis-Jeantet Prize[1] and the I. & H. Wachter Award,[7] in 2005 both the Harvey Prize[8] and the Schleiden Medal, in 2006 the Ernst Schering Prize, and in 2018 the Ernst Jung Gold Medal for Medicine.[1]

Selected publications[]

  • Jap, B.K.; Zulauf, M.; Scheybani, T.; Hefti, A.; Baumeister, W.; Aebi, U.; Engel, A. (1992). "2D crystallization: From art to science". Ultramicroscopy. 46 (1–4): 45–84. doi:10.1016/0304-3991(92)90007-7. PMID 1481277.
  • Guckenberger R.; Hartmann T.; Wiegräbe W.; Baumeister W. (1992). "The Scanning Tunneling Microscope in Biology". In Wiesendanger R.; Güntherodt HJ. (eds.). Scanning Tunneling Microscopy II. Springer Series in Surface Sciences. Vol. 28. Berlin; Heidelberg: Springer. doi:10.1007/978-3-642-97363-5_3. ISBN 978-3-642-97365-9.
  • Koster, Abraham J.; Grimm, Rudo; Typke, Dieter; Hegerl, Reiner; Stoschek, Arne; Walz, Jochen; Baumeister, Wolfgang (1997). "Perspectives of Molecular and Cellular Electron Tomography". Journal of Structural Biology. 120 (3): 276–308. doi:10.1006/jsbi.1997.3933. PMID 9441933.
  • Baumeister, Wolfgang; Walz, Jochen; Zühl, Frank; Seemüller, Erika (1998). "The Proteasome: Paradigm of a Self-Compartmentalizing Protease". Cell. 92 (3): 367–380. doi:10.1016/S0092-8674(00)80929-0. PMID 9476896. S2CID 11225209.
  • Baumeister, W.; Grimm, R.; Walz, J. (1999). "Electron tomography of molecules and cells". Trends in Cell Biology. 9 (2): 81–85. doi:10.1016/S0962-8924(98)01423-8. PMID 10087625.
  • Voges, D.; Zwickl, P.; Baumeister, W. (1999). "The 26S Proteasome: A Molecular Machine Designed for Controlled Proteolysis". Annual Review of Biochemistry. 68: 1015–1068. doi:10.1146/annurev.biochem.68.1.1015. PMID 10872471.
  • Medalia, Ohad; Weber, Igor; Frangakis, Achilleas S.; Nicastro, Daniela; Gerisch, Günther; Baumeister, Wolfgang (2002). "Macromolecular Architecture in Eukaryotic Cells Visualized by Cryoelectron Tomography". Science. 298 (5596): 1209–1213. Bibcode:2002Sci...298.1209M. doi:10.1126/science.1076184. S2CID 16363105.
  • Sali, Andrej; Glaeser, Robert; Earnest, Thomas; Baumeister, Wolfgang (2003). "From words to literature in structural proteomics". Nature. 422 (6928): 216–225. Bibcode:2003Natur.422..216S. doi:10.1038/nature01513. PMID 12634795. S2CID 229310.
  • GrüNewald, Kay; Desai, Prashant; Winkler, Dennis C.; Heymann, J. Bernard; Belnap, David M.; Baumeister, Wolfgang; Steven, Alasdair C. (2003). "Three-Dimensional Structure of Herpes Simplex Virus from Cryo-Electron Tomography". Science. 302 (5649): 1396–1398. Bibcode:2003Sci...302.1396G. doi:10.1126/science.1090284. PMID 14631040. S2CID 362079.
  • Lučić, Vladan; Förster, Friedrich; Baumeister, Wolfgang (2005). "Structural Studies by Electron Tomography: From Cells to Molecules". Annual Review of Biochemistry. 74: 833–865. doi:10.1146/annurev.biochem.73.011303.074112. PMID 15952904.
  • Robinson, Carol V.; Sali, Andrej; Baumeister, Wolfgang (2007). "The molecular sociology of the cell". Nature. 450 (7172): 973–982. Bibcode:2007Natur.450..973R. doi:10.1038/nature06523. PMID 18075576. S2CID 3199789.
  • Beck, Martin; Lučić, Vladan; Förster, Friedrich; Baumeister, Wolfgang; Medalia, Ohad (2007). "Snapshots of nuclear pore complexes in action captured by cryo-electron tomography". Nature. 449 (7162): 611–615. Bibcode:2007Natur.449..611B. doi:10.1038/nature06170. PMID 17851530. S2CID 4411582.
  • Lasker, K.; Forster, F.; Bohn, S.; Walzthoeni, T.; Villa, E.; Unverdorben, P.; Beck, F.; Aebersold, R.; Sali, A.; Baumeister, W. (2012). "Molecular architecture of the 26S proteasome holocomplex determined by an integrative approach". Proceedings of the National Academy of Sciences. 109 (5): 1380–1387. doi:10.1073/pnas.1120559109. PMC 3277140. PMID 22307589.
  • Rigort, A.; Bauerlein, F. J. B.; Villa, E.; Eibauer, M.; Laugks, T.; Baumeister, W.; Plitzko, J. M. (2012). "Focused ion beam micromachining of eukaryotic cells for cryoelectron tomography". Proceedings of the National Academy of Sciences. 109 (12): 4449–4454. Bibcode:2012PNAS..109.4449R. doi:10.1073/pnas.1201333109. PMC 3311327. PMID 22392984.
  • Lučić, Vladan; Rigort, Alexander; Baumeister, Wolfgang (2013). "Cryo-electron tomography: The challenge of doing structural biology in situ". Journal of Cell Biology. 202 (3): 407–419. doi:10.1083/jcb.201304193. PMC 3734081. PMID 23918936.

References[]

  1. ^ a b c d e f g "Curriculum Vitae Professor Dr. Wolfgang Baumeister" (PDF). Leopoldina. 2010.
  2. ^ "Wolfgang Baumeister, Research Department "Molecular Structural Biology"". Max Planck Institute of Biochemistry.
  3. ^ "Prof. Dr. Wolfgang Baumeister". Technical University of Munich (tum.de).
  4. ^ "Biochemical and Biophysical Research Communications". journals.elsevier.com.
  5. ^ "Prof. Dr. Wolfgang P. Baumeister". Bayerisch Akademie der Wissenschaften.
  6. ^ "Mitglieder. Prof. Dr. Wolfgang Baumeister". Leopoldina Nationale Akademie der Wissenschaften.
  7. ^ "Awardee 2003, Prof. Dr. Wolfgang P. Baumeister, for the elucication of the structure and mechanism of the proteasome". Ilse & Helmut Wachter Stiftung at the Medical University Innsbruck.
  8. ^ "Technion Honors". technion.ac.il. 11 August 2015.
Retrieved from ""