Yimon Aye

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Associate professor

Yimon Aye
EPFL Yimon Aye Portrait.jpg
Yimon Aye in 2018
Born1980 (age 41–42)
CitizenshipUS-American
Known forElectrophile signaling
Nucleotide signaling pathways
RelativesSoe Thein (father)
Academic background
EducationChemistry
Alma materUniversity of Oxford
Harvard University
Massachusetts Institute of Technology
Doctoral advisorDavid A. Evans
Other advisorsJoAnne Stubbe
Academic work
DisciplineBiology
Sub-disciplineMolecular Biology
InstitutionsEPFL
Main interestsSynthetic Methodology
Chemical Biology
Biochemistry
Biophysics
Molecular Biology
Cell Biology
Websitehttps://leago.epfl.ch

Yimon Aye (born 1980 in Burma) is an American chemist and molecular biologist.

Career[]

Aye spent her early life in Burma. She completed her undergraduate studies in chemistry at the University of Oxford and obtained her master's degree in 2004.[1] She joined Harvard University to study synthetic organic chemistry with David A. Evans, achieving her PhD in 2009.[2] She then moved to Massachusetts Institute of Technology as a Damon Runyon Cancer Research Foundation fellow to work with JoAnne Stubbe. There she performed research into the regulatory mechanisms of ribonucleotide reductase.[3] In 2012, she started as an assistant professor at Cornell University, where she began her work on redox-dependent cell signaling and genome maintenance pathways. During this time, she developed REX technologies, new methods to facilitate the study of unconventional electrophile-regulated stress signaling paradigms.[4][5] REX technologies were one of the first approaches to forge direct links between upstream protein alteration by a reactive molecule and downstream responses.[2]

In 2018, she was appointed as an Assistant Professor of chemistry at EPFL.[6] Since August 2018, she has been leading the Laboratory of Electrophiles And Genome Operation (LEAGO) of the Institute of Chemical Sciences and Engineering (ISIC) at EPFL.[7]

References[]

  1. ^ admin (2018-01-12). "Interview with Dr.Yimon Aye Assistant Professor of Cornell University". Myanmar Insider. Retrieved 2020-09-21.
  2. ^ a b "2017 WCC Rising Star Dr. Yimon Aye – Corn... | ACS Network". communities.acs.org. Retrieved 2020-09-21.
  3. ^ "JoAnne Stubbe Research Group - MIT". web.mit.edu. Retrieved 2020-09-21.
  4. ^ Poganik, Jesse R.; Long, Marcus J. C.; Aye, Yimon (2019-02-11). "Interrogating Precision Electrophile Signaling". Trends in Biochemical Sciences. 44 (4): 380–381. doi:10.1016/j.tibs.2019.01.006. ISSN 0968-0004. PMC 6462755. PMID 30765181.
  5. ^ Long, Marcus J.C.; Urul, Daniel A.; Aye, Yimon (2020), "REX technologies for profiling and decoding the electrophile signaling axes mediated by Rosetta Stone proteins", Methods in Enzymology, Elsevier, 633: 203–230, doi:10.1016/bs.mie.2019.02.039, ISBN 978-0-12-819128-6, PMC 7027669, PMID 32046846
  6. ^ "15 new professors appointed at the two Federal Institutes of Technology | ETH-Board". www.ethrat.ch. Retrieved 2020-09-21.
  7. ^ "Laboratory of electrophiles and genome operation". www.epfl.ch. Retrieved 2020-09-21.

External links[]

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