ZBED1

From Wikipedia, the free encyclopedia

ZBED1

Protein ZBED1 PDB 2ct5.png

Available structures

Human UniProt search: PDBe RCSB

List of PDB id codes
2CT5

Identifiers

ZBED1, ALTE, DREF, TRAMP, hDREF, zinc finger BED-type containing 1

External IDs

OMIM: 300178 HomoloGene: 123965 GeneCards: ZBED1

Gene location (Human)

Chr.	X chromosome (human)^[1]

Band	X;Y	Start	2,486,414 bp^[1]
Band	X;Y	End	2,500,976 bp^[1]

RNA expression pattern

Top expressed in
adrenal gland gastrocnemius muscle biceps brachii heart myocardium vastus lateralis muscle
More reference expression data

n/a

Gene ontology
Molecular function	DNA binding transposase activity GO:0001948 protein binding protein dimerization activity metal ion binding RNA polymerase II transcription regulatory region sequence-specific DNA binding GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity identical protein binding SUMO transferase activity GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding GO:0001077, GO:0001212, GO:0001213, GO:0001211, GO:0001205 DNA-binding transcription activator activity, RNA polymerase II-specific sequence-specific DNA binding GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific
Cellular component	nuclear chromosome nucleus nucleoplasm
Biological process	regulation of transcription by RNA polymerase II protein sumoylation transcription by RNA polymerase II positive regulation of transcription by RNA polymerase II
Sources:Amigo / QuickGO

Orthologs

Species

Human

Mouse


9189


n/a

Ensembl


ENSG00000214717


n/a


O96006


n/a

RefSeq (mRNA)


NM_004729 NM_001171135 NM_001171136


n/a

RefSeq (protein)


NP_001164606 NP_001164607 NP_004720


n/a

Location (UCSC)

Chr X: 2.49 – 2.5 Mb

n/a

PubMed search

^[2]

n/a

View/Edit Human

Zinc finger BED domain-containing protein 1 is a protein that in humans is encoded by the ZBED1 gene.^[3]^[4]^[5]

References[]

^ ^a ^b ^c GRCh38: Ensembl release 89: ENSG00000214717 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Nagase T, Ishikawa K, Suyama M, Kikuno R, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Apr 1999). "Prediction of the coding sequences of unidentified human genes. XI. The complete sequences of 100 new cDNA clones from brain which code for large proteins in vitro". DNA Res. 5 (5): 277–86. doi:10.1093/dnares/5.5.277. PMID 9872452.
^ Esposito T, Gianfrancesco F, Ciccodicola A, Montanini L, Mumm S, D'Urso M, Forabosco A (Mar 1999). "A novel pseudoautosomal human gene encodes a putative protein similar to Ac-like transposases". Hum Mol Genet. 8 (1): 61–7. doi:10.1093/hmg/8.1.61. PMID 9887332.
^ "Entrez Gene: ZBED1 zinc finger, BED-type containing 1".

Further reading[]

Bonaldo MF, Lennon G, Soares MB (1997). "Normalization and subtraction: two approaches to facilitate gene discovery". Genome Res. 6 (9): 791–806. doi:10.1101/gr.6.9.791. PMID 8889548.
Strausberg RL, Feingold EA, Grouse LH, et al. (2003). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Ohshima N, Takahashi M, Hirose F (2003). "Identification of a human homologue of the DREF transcription factor with a potential role in regulation of the histone H1 gene". J. Biol. Chem. 278 (25): 22928–38. doi:10.1074/jbc.M303109200. PMID 12663651.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature. 437 (7062): 1173–8. doi:10.1038/nature04209. PMID 16189514. S2CID 4427026.
Lim J, Hao T, Shaw C, et al. (2006). "A protein-protein interaction network for human inherited ataxias and disorders of Purkinje cell degeneration". Cell. 125 (4): 801–14. doi:10.1016/j.cell.2006.03.032. PMID 16713569.
Yamashita D, Komori H, Higuchi Y, et al. (2007). "Human DNA replication-related element binding factor (hDREF) self-association via hATC domain is necessary for its nuclear accumulation and DNA binding". J. Biol. Chem. 282 (10): 7563–75. doi:10.1074/jbc.M607180200. PMID 17209048.
Yamashita D, Sano Y, Adachi Y, et al. (2007). "hDREF Regulates Cell Proliferation and Expression of Ribosomal Protein Genes". Mol. Cell. Biol. 27 (6): 2003–13. doi:10.1128/MCB.01462-06. PMC 1820502. PMID 17220279.

v t PDB gallery
2ct5: Solution Structure of the zinc finger BED domain of the zinc finger BED domain containing protein 1

This protein-related article is a stub. You can help Wikipedia by .

Retrieved from ""

Categories:

Genes on human chromosome X
Protein stubs

Hidden categories:

All stub articles