Zinc finger homeobox 2

ZFHX2
Identifiers
Aliases	ZFHX2, ZFH-5, ZNF409, ZFH5, MARSIS, zinc finger homeobox 2
External IDs	OMIM: 617828 MGI: 2686934 HomoloGene: 52657 GeneCards: ZFHX2
Gene location (Human) Chr. Chromosome 14 (human)[1] Band 14q11.2 Start 23,520,857 bp[1] End 23,556,192 bp[1]
Gene location (Mouse) Chr. Chromosome 14 (mouse)[2] Band 14|14 C3 Start 55,297,719 bp[2] End 55,329,781 bp[2]
RNA expression pattern Bgee Top expressed in testicle muscle tissue sural nerve hypothalamus cerebellum cerebellar hemisphere More reference expression data BioGPS n/a
Gene ontology Molecular function sequence-specific DNA binding DNA binding zinc ion binding metal ion binding nucleic acid binding GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific GO:0000980 RNA polymerase II cis-regulatory region sequence-specific DNA binding Cellular component nucleus Biological process adult behavior regulation of transcription, DNA-templated transcription, DNA-templated regulation of transcription by RNA polymerase II negative regulation of transcription by RNA polymerase II positive regulation of transcription, DNA-templated regulation of sensory perception of pain Sources:Amigo / QuickGO
Orthologs
Species	Human	Mouse
Entrez	85446	239102
Ensembl	ENSG00000136367	ENSMUSG00000040721
UniProt	Q9C0A1	Q2MHN3
RefSeq (mRNA)	NM_033400	NM_001039198
RefSeq (protein)	NP_207646	NP_001034287
Location (UCSC)	Chr 14: 23.52 – 23.56 Mb	Chr 14: 55.3 – 55.33 Mb
PubMed search	[3]	[4]
Wikidata
View/Edit Human View/Edit Mouse

Zinc finger homeobox 2 is a protein that in humans is encoded by the ZFHX2 gene.^[5] It has been implicated in pain insensitivity.^[6]

References[]

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