Zinc finger protein 334

ZNF334
Identifiers
Aliases	ZNF334, zinc finger protein 334
External IDs	MGI: 2388656 HomoloGene: 23076 GeneCards: ZNF334
Gene location (Mouse)
Chr.	Chromosome 2 (mouse)
End	165,388,259 bp
Gene ontology
Molecular function	• GO:0001131, GO:0001151, GO:0001130, GO:0001204 DNA-binding transcription factor activity; • DNA binding; • metal ion binding; • nucleic acid binding; • GO:0001948 protein binding; • GO:0001200, GO:0001133, GO:0001201 DNA-binding transcription factor activity, RNA polymerase II-specific;
Cellular component	• intracellular anatomical structure; • nucleus;
Biological process	• regulation of transcription, DNA-templated; • transcription, DNA-templated; • regulation of transcription by RNA polymerase II;
	Sources:Amigo / QuickGO
Orthologs
	55713
	228876
	ENSG00000198185
	ENSMUSG00000017667
	Q9HCZ1
	A2A4U6
	NM_001270497; NM_018102; NM_199441
	NM_178411
NP_001257426; NP_060572; NP_001340742; NP_001340743; NP_001340744;
	NP_001340745; NP_001340746; NP_001340747; NP_001340748; NP_001340749; NP_001340750; NP_001340751; NP_001340752; NP_001340753; NP_001340754; NP_001340755; NP_955473
	NP_848498
	Wikidata
View/Edit Human	View/Edit Mouse

Zinc finger protein 334 is a protein that in humans is encoded by the ZNF334 gene. ^[4]

Function[]

This gene encodes a member of the C2H2 zinc finger family. The encoded protein contains a Krueppel-associated box, fourteen C2H2 zinc finger domains, and four C2H2-type/integrase DNA-binding domains. Decreased expression of this gene may be a marker for rheumatoid arthritis. Alternative splicing results in multiple transcript variants that encode different protein isoforms.

References[]

^ ^a ^b ^c GRCm38: Ensembl release 89: ENSMUSG00000017667 - Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Entrez Gene: Zinc finger protein 334". Retrieved 2016-03-10.

Further reading[]

Henc I, Soroczyńska-Cybula M, Bryl E, Witkowski JM (2015). "The in vitro modulatory effect of TNFα on the mRNA expression and protein levels of zinc finger protein ZNF334 in CD4(+) lymphocytes of healthy people". Acta Biochim. Pol. 62 (1): 113–7. doi:10.18388/abp.2014_857. PMID 25738173.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 20 is a stub. You can help Wikipedia by .

[refGRCm38Ensembl-1] GRCm38: Ensembl release 89: ENSMUSG00000017667 - Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[3] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-4] "Entrez Gene: Zinc finger protein 334". Retrieved 2016-03-10.

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