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The 2005 Dr. Pepper Big 12 Championship Game was held at Reliant Stadium on December 3, 2005. The game saw the Big 12 South champions Texas Longhorns take on the Colorado Buffaloes, winners of the Big 12 North. Texas, undefeated and at #2 in the BCS standings, was looking to travel to the national championship.
Texas defeated Colorado, 70–3. The win was the 8th largest margin of victory in Texas football history, and sent the Longhorns to the BCS title game in Pasadena, where they defeated USC 41–38. The game would also be the last for Colorado head coachGary Barnett, who was replaced on December 15 by Dan Hawkins. Colorado would go on to lose 19–10 to Clemson in the Champs Sports Bowl.