5'-Phosphoribosylformylglycinamidine

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5'-Phosphoribosylformylglycinamidine
Phosphoribosylformylglycinamidine.svg
Names
IUPAC name
[(2R,3S,4R,5R)-5-[(1-Amino-2-formamidoethylidene)amino]-3,4-dihydroxyoxolan-2-yl]methyl dihydrogen phosphate
Identifiers
3D model (JSmol)
ChemSpider
  • InChI=1S/C6H12N3O8P/c7-6(8-1-10)9-4-2(11)3(12)5(16-4)17-18(13,14)15/h1-5,11-12H,(H2,13,14,15)(H3,7,8,9,10)/t2-,3+,4-,5-/m1/s1 checkY
    Key: OKXISSDNJVDCJE-KKQCNMDGSA-N checkY
  • InChI=1/C6H12N3O8P/c7-6(8-1-10)9-4-2(11)3(12)5(16-4)17-18(13,14)15/h1-5,11-12H,(H2,13,14,15)(H3,7,8,9,10)/t2-,3+,4-,5-/m1/s1
    Key: OKXISSDNJVDCJE-KKQCNMDGBB
  • C([C@@H]1[C@H]([C@H]([C@@H](O1)/N=C(/CNC=O)\N)O)O)OP(=O)(O)O
  • O[C@H]1[C@@H](O)[C@H](NC(=N)NC=O)O[C@@H]1OP(=O)(O)O
Properties
C8H16N3O8P
Molar mass 313.20 g/mol
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
checkY  (what is checkY☒N ?)
Infobox references

5'-Phosphoribosylformylglycinamidine (or FGAM) is an intermediate in the synthesis of purines.[1]

References[]

  1. ^ Elliott, W.; Weber, G. (1984). "Proliferation-linked increase in phosphoribosylformylglycinamidine synthetase activity (EC 6.3.5.3)". Cancer Research. 44 (6): 2430–2434. PMID 6722784. S2CID 10908552.
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