Cell ablation
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Cell ablation (also known as tissue ablation) is a biotechnological tool for studying cell lineage. The process consists of selectively destroying cells in an organism.
For example, a laser beam or controllable gene promoter for a toxin gene can be used to destroy a selected amount of cells.[1]
Cell ablation can also be used as a tool to produce transgenic organisms lacking a cell type, and as a cure for certain disorders such as cancer and leukemia.[citation needed]
The term is not to be confused with genetic ablation: a method of modifying DNA in order to disrupt the production of a specific gene.[citation needed]
References[]
- ^ Michiko, Saito; et al. (1 August 2001). "Diphtheria toxin receptor mediated conditional and targeted cell ablation in transgenic mice". Nature Biotechnology. 19 (8): 746–750. doi:10.1038/90795. PMID 11479567.
Categories:
- Genetics experiments
- Cell biology stubs