DEA list of chemicals
The United States Drug Enforcement Administration (DEA) maintains lists regarding the classification of illicit drugs (see DEA Schedules). It also maintains List I of chemicals and List II of chemicals, which contain chemicals that are used to manufacture the controlled substances/illicit drugs. The list is designated within the Controlled Substances Act[1] but can be modified by the U.S. Attorney General as illegal manufacturing practices change.
Although the list is controlled by the Attorney General, the list is considered a DEA list because the DEA publishes and enforces the list.
Suppliers of these products are subject to regulation and control measures:[2]
| Regulation | List I | List II | Tableting and Encapsulating Machines | Special Surveillance List |
|---|---|---|---|---|
| Know your customer | X | X | X | X |
| Annual manufacturing, inventory, and use reports for bulk manufacturers | X | X | X | |
| 15 day advanced DEA notice required for imports, exports, and transshipments | X | X | ||
| 15 day advanced DEA notice required for international transactions | X | X | ||
| Keep transaction records for at least two years | X | X | ||
| Maintain effective security controls | X | X | ||
| Required reporting for unusual sales and losses or sales to DEA-identified companies | X | X | ||
| Registration required for manufacturing, distribution, import, or export | X | |||
| Reports of mail-order sales to non-regulated entities | X |
List I chemicals[]
These chemicals are designated as those that are used in the manufacture of the controlled substances and are important to the manufacture of the substances. The substance or substances that the List I chemicals may be used for manufacturing is in parentheses:[3]
| Chemical | Illicit drug |
|---|---|
| Anthranilic acid, its esters, and its salts | methaqualone and analogues| |
| Benzyl cyanide | phenylacetic acid, phenylacetone, amphetamine |
| Ephedrine, its salts, optical isomers, and salts of optical isomers | methamphetamine |
| Ergonovine and its salts | lysergic acid diethylamide |
| Ergotamine and its salts | lysergic acid diethylamide |
| N-Acetylanthranilic acid, its esters, and its salts | methaqualone |
| Norpseudoephedrine, its salts, optical isomers, and salts of optical isomers | amphetamine |
| Phenylacetic acid, its esters, and its salts | phenylacetone, amphetamine, methamphetamine |
| Phenylpropanolamine, its salts, optical isomers, and salts of optical isomers | amphetamine, methamphetamine |
| Piperidine and its salts | phencyclidine and analogues |
| Pseudoephedrine, its salts, optical isomers, and salts of optical isomers | methamphetamine |
| 3,4-Methylenedioxyphenyl-2-propanone | MDMA, MDA, MDEA, MDOH |
| Methylamine | methamphetamine |
| Ethylamine | etilamfetamine |
| Propionic anhydride | fentanyl |
| Isosafrole | MDA |
| Safrole | MDA |
| Piperonal | MDA |
| N-Methylephedrine, its salts, optical isomers, and salts of optical isomers | methamphetamine |
| N-Methylpseudoephedrine, its salts, optical isomers, and salts of optical isomers | methamphetamine |
| Hydroiodic acid | methamphetamine, amphetamine |
| Benzaldehyde | methamphetamine, amphetamine |
| Nitroethane | methamphetamine, amphetamine |
| Gamma butyrolactone (other names include: GBL; dihydro-2(3H)-furanone; 1,2-butanolide; 1,4-butanolide; 4-hydroxybutanoic acid lactone; gamma-hydroxybutyric acid lactone) | Gamma-Hydroxybutyric acid, GHB |
| Red phosphorus | methamphetamine, amphetamine |
| White phosphorus (other names: yellow phosphorus) | methamphetamine, amphetamine |
| Hypophosphorous acid and its salts (including ammonium hypophosphite, calcium hypophosphite, iron hypophosphite, potassium hypophosphite, manganese hypophosphite, magnesium hypophosphite and sodium hypophosphite) | methamphetamine, amphetamine |
| N-Phenethyl-4-piperidone (NPP) | fentanyl |
| Iodine | methamphetamine, amphetamine |
| Ergocristine and its salts | lysergic acid diethylamide |
List II chemicals[]
These chemicals are designated as those that are used in the manufacture of controlled substances:[3]
- Acetic anhydride
- Acetone
- Benzyl chloride
- Diethyl ether
- Potassium permanganate
- 2-Butanone (or methyl ethyl ketone or MEK)
- Toluene
- Hydrochloric acid (including anhydrous hydrogen chloride)
- Sulfuric acid
- Methyl isobutyl ketone (MIBK)
- Sodium permanganate
Special Surveillance List[]
Chemicals[]
All listed chemicals[4] as specified in 21 CFR 1310.02 (a) or (b). This includes supplements which contain a listed chemical, regardless of their dosage form or packaging and regardless of whether the chemical mixture, drug product or dietary supplement is exempt from regulatory controls. For each chemical, its illicit manufacturing use is given in parentheses. Some Special Surveillance List chemicals do not have an exclusive manufacturing use for a specific illicit drug but rather have a broad range of uses in both legitimate and illicit manufacturing operations.
| Chemical | Illicit drug |
|---|---|
| Ammonia gas | amphetamine, methamphetamine |
| Ammonium formate | amphetamine, methamphetamine |
| Bromobenzene | phencyclidine |
| Carbonyldiimidazole | lysergic acid diethylamide |
| Cyclohexanone | phencyclidine |
| 1,1-Dichloro-1-fluoroethane (aka freon 141B) | |
| Diethylamine and its salts | lysergic acid diethylamide |
| 2,5-Dimethoxyphenethylamine and its salts (2C-B, 2C-C, 2C-I, 2C-N) | |
| Formamide | amphetamine, methamphetamine |
| Formic acid | amphetamine, methamphetamine |
| Lithium metal | amphetamine, methamphetamine |
| Lithium aluminum hydride | amphetamine, methamphetamine |
| Magnesium metal (turnings) | phencyclidine |
| Mercuric chloride | amphetamine, methamphetamine |
| N-Methylformamide | amphetamine, methamphetamine |
| Organomagnesium halides (Grignard reagents) (e.g. ethylmagnesium bromide and phenylmagnesium bromide) | phencyclidine |
| Phenylethanolamine and its salts | |
| Phosphorus pentachloride | lysergic acid diethylamide |
| Potassium dichromate | general-purpose oxidizing agent |
| Pyridine and its salts | general-purpose solvent |
| Sodium dichromate | general-purpose oxidizing agent |
| Sodium metal | phenylacetone |
| Thionyl chloride | lysergic acid diethylamide |
| ortho-Toluidine | methaqualone |
| Trichloromonofluoromethane (aka freon-11, carrene-2) | |
| 1,1,2-Trichloro-1,2,2-trifluoroethane (aka freon 113) |
Equipment[]
The equipment list:[4]
- Hydrogenators
- Tableting machines
- Encapsulating machines
- 22-liter heating mantles
References[]
- ^ 21 U.S.C. § 802, paragraphs 34 (list I) and 35 (list II)
- ^ DEA (2013). "Chemical Handler's Manual" (PDF). usdoj.gov. Archived from the original (PDF) on 2017-04-27. Retrieved 2017-05-05.
- ^ a b "Archived copy". Archived from the original on December 15, 2014. Retrieved August 28, 2014.CS1 maint: archived copy as title (link)
- ^ a b "Archived copy". Archived from the original on April 20, 2011. Retrieved May 20, 2011.CS1 maint: archived copy as title (link)
External links[]
See also[]
- Drug Enforcement Administration
- Chemistry-related lists
- Drug control law in the United States
- Regulation of chemicals
- Regulation in the United States