Diroximel fumarate

Diroximel fumarate
Clinical data
Trade names	Vumerity
Other names	ALKS-8700
AHFS/Drugs.com	Monograph
MedlinePlus	a620002
License data	US DailyMed: Diroximel_fumarate;
Routes of; administration	By mouth
ATC code	None;
Legal status
Legal status	US: ℞-only ;
Identifiers
CAS Number	1577222-14-0;
PubChem CID	73330464;
DrugBank	DB14783;
ChemSpider	57423290;
UNII	K0N0Z40J3W;
KEGG	D11154;
ChEMBL	ChEMBL3989944;
Chemical and physical data
Formula	C11H13NO6
Molar mass	255.226 g·mol−1
3D model (JSmol)	Interactive image;
	show SMILES
	show InChI

Diroximel fumarate, sold under the brand name Vumerity, is a medication used for the treatment of relapsing forms of multiple sclerosis (MS).^[1]^[2]^[3]

Diroximel fumarate was approved for medical use in the United States in October 2019.^[4] This drug was formulated by Alkermes in collaboration with Biogen.^[5]

References[]

^ Jump up to: ^a ^b "Vumerity- diroximel fumarate capsule". DailyMed. Retrieved 1 February 2021.
^ Wang Y, Bhargava P (July 2020). "Diroximel fumarate to treat multiple sclerosis". Drugs of Today (Barcelona, Spain : 1998). 56 (7): 431–437. doi:10.1358/dot.2020.56.7.3151521. PMID 32648853.
^ Kourakis S, Timpani CA, de Haan JB, Gueven N, Fischer D, Rybalka E (October 2020). "Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?". Pharmaceuticals (Basel, Switzerland). 13 (10): 306. doi:10.3390/ph13100306. PMC 7602023. PMID 33066228.
^ "Drug Approval Package: Vumerity". U.S. Food and Drug Administration (FDA). 21 April 2020. Retrieved 1 February 2021.
^ "Diroximel fumarate".

External links[]

"Diroximel fumarate". Drug Information Portal. U.S. National Library of Medicine.

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[Vumerity_FDA_label-1] Jump up to: ^a ^b "Vumerity- diroximel fumarate capsule". DailyMed. Retrieved 1 February 2021.

[pmid32648853-2] Wang Y, Bhargava P (July 2020). "Diroximel fumarate to treat multiple sclerosis". Drugs of Today (Barcelona, Spain : 1998). 56 (7): 431–437. doi:10.1358/dot.2020.56.7.3151521. PMID 32648853.

[pmid33066228-3] Kourakis S, Timpani CA, de Haan JB, Gueven N, Fischer D, Rybalka E (October 2020). "Dimethyl Fumarate and Its Esters: A Drug with Broad Clinical Utility?". Pharmaceuticals (Basel, Switzerland). 13 (10): 306. doi:10.3390/ph13100306. PMC 7602023. PMID 33066228.

[4] "Drug Approval Package: Vumerity". U.S. Food and Drug Administration (FDA). 21 April 2020. Retrieved 1 February 2021.

[5] "Diroximel fumarate".

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