FANC proteins
FANC proteins are a group of proteins associated with Fanconi anemia.[1][2][3]
They are involved in DNA replication and damage response.[4]
Components include:
- core protein complex (FANCA, FANCB, FANCC, FANCE, FANCF, FANCG, FANCL, FANCM)
- other: FANCD1, FANCD2, FANCI, FANCJ, FANCN, FANCP
References[]
- ^ FANC+Proteins at the US National Library of Medicine Medical Subject Headings (MeSH)
- ^ Naim V, Rosselli F (June 2009). "The FANC pathway and BLM collaborate during mitosis to prevent micro-nucleation and chromosome abnormalities". Nat. Cell Biol. 11 (6): 761–8. doi:10.1038/ncb1883. PMID 19465921. S2CID 330040.
- ^ Hans D. Ochs; C. I. Edvard Smith; Jennifer Puck (2007). Primary immunodeficiency diseases: a molecular and genetic approach. Oxford University Press US. pp. 431–. ISBN 978-0-19-514774-2. Retrieved 21 December 2010.
- ^ Naim V, Rosselli F (September 2009). "The FANC pathway and mitosis: a replication legacy". Cell Cycle. 8 (18): 2907–11. doi:10.4161/cc.8.18.9538. PMID 19729998.
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- DNA repair
- Protein families
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