Fischer–Hepp rearrangement
Fischer-Hepp rearrangement | |
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Named after | Eduard Hepp |
Reaction type | Rearrangement reaction |
Identifiers | |
RSC ontology ID | RXNO:0000095 |
The Fischer–Hepp rearrangement is a rearrangement reaction in which an aromatic N-nitroso or nitrosamine converts to a carbon nitroso compound:[1][2]
This organic reaction was first described by the German chemist (1852–1932) and Eduard Hepp (June 11, 1851 – June 18, 1917) [3] in 1886, and is of importance because para-NO secondary anilines cannot be prepared in a direct reaction.
The rearrangement reaction takes place by reacting the nitrosamine precursor with hydrochloric acid. The chemical yield is generally good under these conditions, but often much poorer if a different acid is used. The exact reaction mechanism is unknown but there is evidence suggesting an intramolecular reaction.
Sources[]
- Named Things in Chemical Industry[dead link]
See also[]
- Friedel–Crafts alkylation-like reactions:
- Hofmann-Martius rearrangement
- Fries rearrangement
References[]
Categories:
- Rearrangement reactions
- Name reactions