Idursulfase
| Clinical data | |
|---|---|
| AHFS/Drugs.com | Monograph |
| License data | |
| ATC code | |
| Identifiers | |
| CAS Number | |
| DrugBank | |
| ChemSpider |
|
| UNII | |
| KEGG | |
| ChEMBL | |
  (what is this?) | |
Idursulfase (brand name Elaprase), manufactured by Takeda, is a drug used to treat Hunter syndrome (also called MPS-II).[1] It is a purified form of the lysosomal enzyme iduronate-2-sulfatase and is produced by recombinant DNA technology in a human cell line.
It is one of the most expensive drugs ever produced, costing US$567,412 per patient per year.[2][3][4]
References[]
- ^ Garcia AR, DaCosta JM, Pan J, Muenzer J, Lamsa JC (2007). "Preclinical dose ranging studies for enzyme replacement therapy with idursulfase in a knock-out mouse model of MPS II". Mol. Genet. Metab. 91 (2): 183–90. doi:10.1016/j.ymgme.2007.03.003. PMID 17459751.
- ^ "Drug approved to treat rare but potentially deadly disease". Archived from the original on 2011-02-24. Retrieved 2011-04-29.
- ^ Health Care: The World's Most Expensive Drugs, Matthew Herper, Forbes, Feb. 22, 2010
- ^ [1], Barbara Kollmeyer, Marketwatch, Fed. 3, 2016
External links[]
- idursulfase at the US National Library of Medicine Medical Subject Headings (MeSH)
 | This drug article relating to the gastrointestinal system is a stub. You can help Wikipedia by . |
Categories:
- Orphan drugs
- Gastrointestinal system drug stubs