Mantle zone
Mantle zone | |
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![]() Image labeled in German, but "Mantel-zone" visible near center. | |
Anatomical terminology |
The mantle zone (or just mantle) of a lymphatic nodule (or lymphatic follicle) is an outer ring of small lymphocytes surrounding a germinal center.[1]
It is also known as the "corona".[2]
It contains transient lymphocytes.[3]
It is the location of the lymphoma in mantle cell lymphoma.
Pathology[]
![](http://upload.wikimedia.org/wikipedia/commons/thumb/4/40/Castleman_disease_-_intermed_mag.jpg/220px-Castleman_disease_-_intermed_mag.jpg)
Intermediate magnification micrograph of Castleman disease showing the characteristic expansion of the mantle zone. H&E stain.
Mantle zone expansion may be seen in benign, such as Castleman disease, and malignancy, i.e., Mantle cell lymphoma. Tcl-1 is expressed in the mantle zone.
References[]
- ^ "Archived copy". Archived from the original on 2008-06-03. Retrieved 2008-07-29.
{{cite web}}
: CS1 maint: archived copy as title (link) - ^ "Archived copy". Archived from the original on 2008-03-17. Retrieved 2008-07-29.
{{cite web}}
: CS1 maint: archived copy as title (link) - ^ http://www.dartmouth.edu/~nlevy/levylecture.html
External links[]
- https://web.archive.org/web/20080813003821/http://erl.pathology.iupui.edu/HISTO/LABE109.HTM
- Histology image: 07102loa – Histology Learning System at Boston University — "Lymphoid Tissues and Organs: lymph node, cortex and medulla"
Categories:
- Lymphatic organ anatomy