Myosmine

Myosmine
Names
	Preferred IUPAC name 3-(3,4-Dihydro-2H-pyrrol-5-yl)pyridine
	Other names 3-(1-Pyrrolin-2-yl)pyridine
Identifiers
CAS Number	532-12-7 ;
3D model (JSmol)	Interactive image;
ChemSpider	391011;
ECHA InfoCard	100.165.015
PubChem CID	442649;
UNII	9O0A545W4L ;
CompTox Dashboard (EPA)	DTXSID70891866 ;
	InChI InChI=1S/C9H10N2/c1-3-8(7-10-5-1)9-4-2-6-11-9/h1,3,5,7H,2,4,6H2;
	SMILES n1cccc(c1)/C2=N/CCC2;
Properties
Chemical formula	C9H10N2
Molar mass	146.193 g·mol−1
	Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
	Infobox references

Myosmine is an alkaloid found in tobacco and other plants.^[1] Chemically, it is closely related to nicotine. It inhibits aromatase seven fold more potently than nicotine.^[2] It also releases dopamine in adult but not adolescent rats.^[3]

References[]

^ Tyroller, Stefan; Zwickenpflug, Wolfgang; Richter, Elmar (2002). "New Sources of Dietary Myosmine Uptake from Cereals, Fruits, Vegetables, and Milk". Journal of Agricultural and Food Chemistry. 50 (17): 4909–15. doi:10.1021/jf020281p. PMID 12166981.
^ Doering IL, Richter E (April 2009). "Inhibition of human aromatase by myosmine". Drug Metabolism Letters. 3 (2): 83–6. doi:10.2174/187231209788654045. PMID 19601869.
^ Marusich JA, Darna M, Wilson AG, Denehy ED, Ebben A, Deaciuc AG, Dwoskin LP, Bardo MT, Lefever TW, Wiley JL, Reissig CJ, Jackson KJ (November 2017). "Tobacco's minor alkaloids: Effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats". European Journal of Pharmacology. 814: 196–206. doi:10.1016/j.ejphar.2017.08.029. PMC 6563910. PMID 28844873.

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[1] Tyroller, Stefan; Zwickenpflug, Wolfgang; Richter, Elmar (2002). "New Sources of Dietary Myosmine Uptake from Cereals, Fruits, Vegetables, and Milk". Journal of Agricultural and Food Chemistry. 50 (17): 4909–15. doi:10.1021/jf020281p. PMID 12166981.

[pmid19601869-2] Doering IL, Richter E (April 2009). "Inhibition of human aromatase by myosmine". Drug Metabolism Letters. 3 (2): 83–6. doi:10.2174/187231209788654045. PMID 19601869.

[pmid28844873-3] Marusich JA, Darna M, Wilson AG, Denehy ED, Ebben A, Deaciuc AG, Dwoskin LP, Bardo MT, Lefever TW, Wiley JL, Reissig CJ, Jackson KJ (November 2017). "Tobacco's minor alkaloids: Effects on place conditioning and nucleus accumbens dopamine release in adult and adolescent rats". European Journal of Pharmacology. 814: 196–206. doi:10.1016/j.ejphar.2017.08.029. PMC 6563910. PMID 28844873.

[1]

[2]

[3]

Myosmine

See also[]

References[]