Nuclear atypia
![](http://upload.wikimedia.org/wikipedia/commons/thumb/4/48/Glioblastoma_with_extreme_nuclear_enlargement_-_very_high_mag.jpg/220px-Glioblastoma_with_extreme_nuclear_enlargement_-_very_high_mag.jpg)
Nuclear atypia refers to abnormal appearance of cell nuclei. It is a term used in cytopathology and histopathology. Atypical nuclei are often pleomorphic.
Nuclear atypia can be seen in reactive changes, pre-neoplastic changes and malignancy. Severe nuclear atypia is, in most cases, considered an indicator of malignancy.
See also[]
- Arias-Stella reaction
- NC ratio
- Nuclear pleomorphism
Categories:
- Pathology stubs
- Pathology