p-Chlorocresol

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p-Chlorocresol
P-Chlorocresol.png
Names
Preferred IUPAC name
4-Chloro-3-methylphenol
Other names
p-chloro-m-cresol; PCMC; Preventol; CMK
Identifiers
3D model (JSmol)
ChEBI
ChEMBL
ChemSpider
ECHA InfoCard 100.000.392 Edit this at Wikidata
EC Number
  • 200-431-6
KEGG
RTECS number
  • GO7100000
UNII
UN number 2669
  • InChI=1S/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3 ☒N
    Key: CFKMVGJGLGKFKI-UHFFFAOYSA-N ☒N
  • InChI=1/C7H7ClO/c1-5-4-6(9)2-3-7(5)8/h2-4,9H,1H3
    Key: CFKMVGJGLGKFKI-UHFFFAOYAE
  • Oc1ccc(Cl)c(C)c1
Properties
C7H7ClO
Molar mass 142.58 g·mol−1
Appearance White/pink solid
Odor Phenolic
Density 1.37 g/cm3 (20 °C)
Melting point 55.55 °C (131.99 °F; 328.70 K)
Boiling point 235 °C (455 °F; 508 K)
3.8 g/l at 20 °C (in water)
Hazards
GHS labelling:
GHS05: CorrosiveGHS07: Exclamation markGHS09: Environmental hazard
Signal word
 Danger
H302, H314, H317, H335, H400, H412
P260, P261, P264, P270, P271, P272, P273, P280, P301+P312, P301+P330+P331, P302+P352, P303+P361+P353, P304+P340, P305+P351+P338, P310, P312, P321, P330, P333+P313, P363, P391, P403+P233, P405, P501
Flash point 118 °C (244 °F; 391 K)
Related compounds
Related compounds
 Chloroxylenol (4-chloro-3,5-dimethylphenol)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

p-Chlorocresol is the organic compound with the formula ClC6H4OH. It is a monochlorinated m-cresol. It is a white or colorless solid that is only slightly soluble in water. As a solution in alcohol and in combination with other phenols, it is used as an antiseptic and preservative.[1][2] It is a moderate allergen for sensitive skin.[3]

p-Chlorocresol is prepared by chlorination of m-cresol.[4][5]

Safety[]

With LD50(oral, rat) of 5129 mg/kg, it is weakly toxic.[4]

See also[]

References[]

  1. ^ Susan C Smolinske (1992), Handbook of Food, Drug, and Cosmetic Excipients, p. 87
  2. ^ C. Glen Mayhall (2004), Hospital Epidemiology and Infection Control, p. 1741
  3. ^ Howard I. Maibach (2001), Toxicology of Skin, p. 339
  4. ^ a b Helmut Fiege; Heinz-Werner Voges; Toshikazu Hamamoto; Sumio Umemura; Tadao Iwata; Hisaya Miki; Yasuhiro Fujita; Hans-Josef Buysch; Dorothea Garbe (2007). "Phenol Derivatives". Ullmann's Encyclopedia of Industrial Chemistry. Weinheim: Wiley-VCH. doi:10.1002/14356007.a19_313.
  5. ^ Commission, British Pharmacopoeia (2009), "Phenoxyethanol", British Pharmacopoeia, 2, ISBN 978-0-11-322799-0
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