Salicylanilide

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Salicylanilide[1]
Salicylanilide.svg
Names
Preferred IUPAC name
2-Hydroxy-N-phenylbenzamide
Other names
2-Hydroxybenzanilide
Identifiers
3D model (JSmol)
ChemSpider
ECHA InfoCard 100.001.571 Edit this at Wikidata
UNII
Properties
C13H11NO2
Molar mass 213.236 g·mol−1
Appearance White to off-white crystalline solid
Melting point 136 to 138 °C (277 to 280 °F; 409 to 411 K)
Hazards
EU classification (DSD) (outdated)
Xi
R-phrases (outdated) R36/37/38
S-phrases (outdated) S36/37/39
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references

Salicylanilide is a chemical compound which is the amide of salicylic acid and aniline. It is classified as both a salicylamide and an anilide.[2]

Derivatives of salicylanilide have a variety of pharmacological uses. Chlorinated derivatives including niclosamide, oxyclozanide, and rafoxanide are used as anthelmintics, especially as flukicides. Brominated derivatives including , , and are used as disinfectants with antibacterial and antifungal activities.

Uses[]

Salicylanilides may be used as antiseptics.

References[]

  1. ^ Salicylanilide at chemicalland21.com
  2. ^ Salicylanilides at the US National Library of Medicine Medical Subject Headings (MeSH)
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