Small Cajal body specific RNA 25

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Small Cajal body specific RNA 3
SCARNA3
Identifiers
SymbolSCARNA3
RfamRF00565
Other data
RNA typeGene; snRNA; snoRNA; scaRNA;
PDB structuresPDBe

Small Cajal body specific RNA 25 (otherwise known as scaRNA25, HBI-100, MBI-100, and MBI-114) is a scaRNA, which are a class of ncRNAs characterised as small nuclear RNAs localised to the Cajal bodies.[1]

ScaRNA25 was originally identified in a large scale cloning project in mice.[2] Later sequence analysis predicted that this RNA guides the pseudouridylation of position U40 in the U6 snRNA.[2]

References[]

  1. ^ Darzacq, Xavier; Jády, Beáta E.; Verheggen, Céline; Kiss, Arnold M.; Bertrand, Edouard; Kiss, Tamás (2002). "Cajal body-specific small nuclear RNAs: A novel class of 2'-O-methylation and pseudouridylation guide RNAs". The EMBO Journal. 21 (11): 2746–2756. doi:10.1093/emboj/21.11.2746. PMC 126017. PMID 12032087.
  2. ^ a b Huttenhofer, Alexander; Kiefmann, Martin; Meier-Ewert, Sebastian; O'Brien, John; Lehrach, Hans; Bachellerie, Jean-Pierre; Brosius, Jürgen (1 June 2001). "RNomics: an experimental approach that identifies 201 candidates for novel, small, non-messenger RNAs in mouse". The EMBO Journal. 20 (11): 2943–2953. doi:10.1093/emboj/20.11.2943. PMC 125495. PMID 11387227.

External links[]


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