VT 243 continues off of Route 243 (Route de Mansonville) at the US-Canadian border near the North Troy–Highwater Border CrossingUnited States Customs station and remains a two lane road its entire length. It proceeds southeast through the dense woods and runs parallel with the eponymous railway, passing by some homes. It intersects with Dominion Avenue, which dead-ends short of the Canada–United States border and becomes Railroad Street as it enters the village of North Troy. It also intersects Elm Street and School Street before making a sharp right turn to the south and becoming South Street as it passes through the neighborhood. The route intersects Main Street before reaching its southern terminus at VT 105 (North Pleasant Street).[2]