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Bexlosteride Other names LY 300502 Routes of administration Oral ATC code Legal status
(4aR ,10bR )-8-Chloro-4-methyl-1,4,4a,5,6,10b-hexahydrobenzo[f ]quinolin-3(2H )-one
CAS Number PubChem CID ChemSpider UNII ChEMBL Formula C 14 H 16 Cl N O Molar mass 249.74 g·mol−1 3D model (JSmol )
CN1[C@@H]2CCc3cc(ccc3[C@H]2CCC1=O)Cl
InChI=1S/C14H16ClNO/c1-16-13-6-2-9-8-10(15)3-4-11(9)12(13)5-7-14(16)17/h3-4,8,12-13H,2,5-7H2,1H3/t12-,13-/m1/s1
Y Key:WQBIOEFDDDEARX-CHWSQXEVSA-N
Y
N Y (what is this?)
Bexlosteride is a potent and noncompetitive inhibitor of the enzyme 5α-reductase related to finasteride and dutasteride .[1] [2] It is selective for the type I isoform of the enzyme.[1] It advanced to Phase III clinical trials , but development was halted at that stage, and it was never marketed.[3] [4]
See also [ ]
References [ ]
Drugs used in benign prostatic hyperplasia (G04C )
5α-Reductase inhibitors Alpha-1 blockers
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Categories :
Drugs not assigned an ATC code 5α-Reductase inhibitors Delta-lactams Chloroarenes Hidden categories:
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