SC 194 begins at an intersection with U.S. Route 378 (US 378; North Jennings Street and Travis Avenue) in Saluda, within Saluda County. It travels to the north and almost immediately curves to the northeast before leaving the city limits. The highway crosses over Burnets Creek and Big Creek. Farther to the northeast is a crossing of Indian Creek, just before an intersection with SC 395 (Kempson Bridge Road). The highway then curves to the southeast and goes in an easterly direction to meet its eastern terminus, an intersection with SC 391 (Prosperity Highway), at a point south of .[2]