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Charles "Lucky" Luciano begins employing Louis "Lepke" Buchalter's "The Combination (called Murder, Inc. by the press) for National Crime Syndicate murder contracts.
Sicilian mafiosi Vito Cascio Ferro dies in Rome, Italy while in prison.
February 9 – Renegade hitman Vincent "Mad Dog" Coll is killed in a drive-by shooting at a public telephone booth while attempting to extort money from mob boss Owney "Killer" Madden.
July 29 – Pittsburgh bootleggers John, Arthur, and James Volpe are shot to death in a Pittsburgh coffee shop. The hits were reportedly ordered by Pittsburgh crime family leader .
August 8 – John Bazzano is found stuffed in a burlap sack on a Brooklyn street He had been strangled, then stabbed to death. Bazzano's murder may have been connected to the gangland slaying of the Volpe brothers weeks earlier. would later succeed Bazzano as head of the Pittsburgh crime family.
September 1 – New York Mayor James J. Walker resigns from office, following his testimony before the Seabury Commission.
