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January 3 – William J. "Wild Bill" Lovett, leader of the New York City White Hand Gang, is shot twice in the chest by in a Brooklyn shanty. Although he eventually recovers from his wounds, he refuses to identify his attackers.
August 28 – "Kid Dropper" Kaplan is killed by Little Augies' gunman Louis Cohen while being transported from Essex Market Court.
September 7 – In a continuing bootlegger war in South Side, Chicago, between the Southside O'Donnell Brothers and an alliance of the Saltis-McErlane Gang and the Chicago Outfit, Saltis-McErlane leader Frank McErlane kills Jerry O'Connor, a member of the Southside O'Donnell Brothers, in a driveby shooting. McErlane is the first to use a Thompson submachine gun, which becomes popularly known as a "Tommy Gun".
September 17 – "Tommy Gun" innovator Frank McErlane kills again, gunning down George Meegan and George Bucher of the Southside O'Donnell Brothers.
November 1 – Having survived the January 3 assassination attempt, White Hand Gang leader "Wild Bill" Lovett is killed by three Black Hand assassins led by Dui Cuteddi.
December 1 – Frank McErlane strikes again, killing Thomas Keane, a beer-runner for the Southside O'Donnell Brothers.