The 2021–22 season is the 108th season in the existence of NK Lokomotiva Zagreb and the club's 13th consecutive season in the top flight of Croatian football. In addition to the domestic league, NK Lokomotiva Zagreb will participate in this season's edition of the Croatian Cup.
Updated to match(es) played on 27 February 2022. Source: PrvaHNL.hr Rules for classification: 1) Points; 2) Head-to-head points; 3) Head-to-head goal difference; 4) Head-to-head goals scored (at home if two teams tied); 5) Goal difference; 6) Goals scored; 7) Play-off (Note: Criteria 2-4 and 7 is only used if deciding champion, teams to international competition or teams for relegation and in that case criteria 6 will not be used).[2]