vaccine
Androvax , also known as androstenedione:human serum albumin conjugate , is an immunogen and vaccine against androstenedione that is used in veterinary medicine to increase the ovulation rate and number of lambs born to ewes .[1] [2] [3] It is a conjugate of androstenedione and human serum albumin .[1] [3] The drug is marketed in New Zealand .[1] [3]
Androvax produces immunity against androstenedione, and the generation of antibodies against androstenedione decreases circulating levels of androstenedione.[1] In addition, since androstenedione is the major precursor of estrogens , estrogen levels are decreased as well.[1] This is thought to result in reduced negative feedback on the hypothalamic-pituitary-gonadal axis and increased gonadotropin secretion , which in turn improves fertility and fecundity .[1]
See also [ ]
References [ ]
Androgens and antiandrogens
Androgens (incl. AAS )
AR agonists
17α-Ethynyltestosterone derivatives: Danazol
Gestrinone
Progestins (e.g., ethisterone (ethynyltestosterone) , levonorgestrel , norgestrel , norethisterone (norethindrone) , lynestrenol , norgestrienone )
Tibolone
Progesterone derivatives: Medroxyprogesterone acetate
Progonadotropins
Antiestrogens (e.g., tamoxifen , clomifene )
GnRH agonists (e.g., GnRH (gonadorelin) , leuprorelin )
Gonadotropins (e.g., LH , hCG )
Antiandrogens
AR antagonists Steroidogenesis inhibitors
Antigonadotropins
D2 receptor antagonists (prolactin releasers ) (e.g., domperidone , metoclopramide , risperidone , haloperidol , chlorpromazine , sulpiride )
Estrogens (e.g., bifluranol , diethylstilbestrol , estradiol , estradiol esters , ethinylestradiol , ethinylestradiol sulfonate , paroxypropione )
GnRH agonists (e.g., leuprorelin )
GnRH antagonists (e.g., cetrorelix )
Progestogens (incl., chlormadinone acetate , cyproterone acetate , hydroxyprogesterone caproate , gestonorone caproate , medroxyprogesterone acetate , megestrol acetate )
Others
Estrogens
ER agonists
Steroidal: Alfatradiol
Certain androgens /anabolic steroids (e.g., testosterone , testosterone esters , methyltestosterone , metandienone , nandrolone esters ) (via estrogenic metabolites)
Certain progestins (e.g., norethisterone , noretynodrel , etynodiol diacetate , tibolone )
Clomestrone
Cloxestradiol acetate
Conjugated estriol
Conjugated estrogens
Epiestriol
Epimestrol
Esterified estrogens
Estetrol †
Estradiol
Estradiol esters (e.g., estradiol acetate , estradiol benzoate , estradiol cypionate , estradiol enanthate , estradiol undecylate , estradiol valerate , polyestradiol phosphate , estradiol ester mixtures (Climacteron ))
Estramustine phosphate
Estriol
Estriol esters (e.g., estriol succinate , polyestriol phosphate )
Estrogenic substances
Estrone
Estrone esters
Ethinylestradiol #
Hydroxyestrone diacetate
Mestranol
Methylestradiol
Moxestrol
Nilestriol
Prasterone (dehydroepiandrosterone; DHEA)
Promestriene
Quinestradol
Quinestrol
Progonadotropins
Antiandrogens (e.g., bicalutamide )
GnRH agonists (e.g., GnRH (gonadorelin) , leuprorelin )
Gonadotropins (e.g., FSH , LH )
Antiestrogens
ER antagonists (incl. SERMs /SERDs )
Exclusively antagonistic: Fulvestrant
Noncompetitive inhibitors: Trilostane
Aromatase inhibitors Antigonadotropins
Androgens /anabolic steroids (e.g., testosterone , testosterone esters , nandrolone esters , oxandrolone , fluoxymesterone )
D2 receptor antagonists (prolactin releasers) (e.g., domperidone , metoclopramide , risperidone , haloperidol , chlorpromazine , sulpiride )
GnRH agonists (e.g., leuprorelin , goserelin )
GnRH antagonists (e.g., cetrorelix , elagolix )
Progestogens (e.g., chlormadinone acetate , cyproterone acetate , gestonorone caproate , hydroxyprogesterone caproate , medroxyprogesterone acetate , megestrol acetate )
Others
Mixed mechanism of action: Danazol
Gestrinone
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III
See also
Estrogen receptor modulators
Androgens and antiandrogens
Progestogens and antiprogestogens
List of estrogens
Artificial induction of immunity /
Immunization :
Vaccines ,
Vaccination ,
Infection ,
Inoculation (
J07 )
Development Classes Administration Vaccines
Bacterial
Anthrax
Brucellosis
Cholera #
Diphtheria #
Hib #
Leptospirosis
Lyme disease ‡
Meningococcus #
Pertussis #
Plague
Pneumococcal #
Q fever
Tetanus #
Tuberculosis
Typhoid #
Typhus
combination:
research:
Clostridioides difficile
Group B streptococcal disease
Shigellosis
Viral Protozoan Helminthiasis Other
Inventors/ researchers
Edward Jenner
Louis Pasteur
Hilary Koprowski
Jonas Salk
John Franklin Enders
Maurice Hilleman
Stanley Plotkin
H. Fred Clark
Paul Offit
Katalin Karikó
Drew Weissman
Controversy
General
MMR (Lancet MMR autism fraud )
NCVIA
Infection party
Thiomersal
Vaccines and SIDS
Cedillo v. Secretary of Health and Human Services
Alternative vaccination schedule
Related
Epidemiology
Eradication of infectious diseases
Every Child By Two
List of vaccine topics
# WHO-EM
‡ Withdrawn from market
Clinical trials :
† Phase III
§ Never to phase III