Quebec Route 221

Route 221
Route 221
Route information
	Maintained by Transports Québec
Length	64.3 km (40.0 mi)
Major junctions
South end	NY 276 in Champlain, New York
	Route 202 in Lacolle ; Route 219 in Napierville ; A-15 / Route 217 / Route 219 in Saint-Cyprien de Napierville ; Route 219 in Saint-Patrice-de-Sherrington ; Route 209 in Saint-Rémi
North end	Route 207 in Saint-Isidore
Highway system
	Quebec provincial highways; Autoroutes; List; Former;

Route 221 is a north/south highway on the south shore of the St. Lawrence River, linking the Canada–US border south of Lacolle to Saint-Isidore.

The highway begins at the Canada–US border at the Overton Corners–Lacolle 221 Border Crossing, where it connects to New York State Route 276, and goes north, having a brief concurrency with Route 202 before reaching the urban area of Lacolle. It then continues north until Napierville where it goes West concurrently with Route 219 until they separate at Saint-Patrice-de-Sherrington, where Route 221 goes north toward Saint-Édouard. There it briefly goes roughly west via Saint-Michel and Saint-Rémi before turning Northeast toward its terminus at Route 207 in the northern part of Saint-Isidore, just south of Autoroute 30.