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Trolnitrate
Names
IUPAC name
2-[bis(2-nitrooxyethyl)amino]ethyl nitrate
Identifiers
3D model (JSmol )
ChemSpider
ECHA InfoCard
100.027.615
UNII
InChI=1S/C6H12N4O9/c11-8(12)17-4-1-7(2-5-18-9(13)14)3-6-19-10(15)16/h1-6H2
Y Key: HWKQNAWCHQMZHK-UHFFFAOYSA-N
Y
C(CO[N+](=O)[O-])N(CCO[N+](=O)[O-])CCO[N+](=O)[O-]
Properties
C6 H12 N4 O9
Molar mass
284.18 g/mol
Pharmacology
C01DA09 (WHO )
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
N (what is Y N ?)
Infobox references
Chemical compound
Trolnitrate is an organic nitrate with vasodilator activity that is used to prevent or ameliorate attacks of angina pectoris.[1] Trolnitrate dilates the coronary vessels because of its basic action as a smooth muscle depressant, just as do nitroglycerin and other organic nitrates.[2]
References [ ]
Forms Targets
NO donors (prodrugs ) Enzyme (inhibitors )
Others
Indirect/downstream NO modulators: ACE inhibitors /AT-II receptor antagonists (e.g., captopril , losartan )
ETB receptor antagonists (e.g., bosentan )
L-Type calcium channel blockers (e.g., dihydropyridines : nifedipine )
Nebivolol (beta blocker )
PDE5 inhibitors (e.g., sildenafil )
non-selective PDE inhibitors (e.g., caffeine )
PDE9 inhibitors (e.g., paraxanthine )
cGMP preferring PDE inhibitors (e.g., sildenafil, paraxanthine, tadalafil)
Statins (e.g., simvastatin )
See also: Receptor/signaling modulators
Categories :
Nitrate esters Cardiovascular system drug stubs Hidden categories:
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