The 1978 African Cup of Nations Final was a football match that took place on 16 March 1978, at the Accra Sports Stadium in Accra, Ghana, to determine the winner of the 1978 Africa Cup of Nations. Ghana defeated Uganda 2–0 with two goals from Opoku Afriyie to win their third African Cup. As of 2019, this is the only Ugandan appearance in an African Cup of Nations final.
No qualification took place in 1957 and 1959 as places were given by invitation only. In 1959 and 1976, there was no final; the article is about the decisive match of the final group stage.