Acetarsol

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Acetarsol
Kekulé, skeletal formula of acetarsol
Names
Preferred IUPAC name
(3-Acetamido-4-hydroxyphenyl)arsonic acid
Other names
Acetarsone
Identifiers
3D model (JSmol)
ChEMBL
ChemSpider
ECHA InfoCard 100.002.349 Edit this at Wikidata
EC Number
  • 202-582-3
KEGG
MeSH Acetarsol
UNII
UN number 3465
  • InChI=1S/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15) checkY
    Key: ODFJOVXVLFUVNQ-UHFFFAOYSA-N checkY
  • InChI=1/C8H10AsNO5/c1-5(11)10-7-4-6(9(13,14)15)2-3-8(7)12/h2-4,12H,1H3,(H,10,11)(H2,13,14,15)
    Key: ODFJOVXVLFUVNQ-UHFFFAOYAX
  • CC(=O)Nc1cc(ccc1O)[As](O)(O)=O
  • CC(=O)NC1=CC(=CC=C1O)[As](O)(O)=O
Properties
C8H10AsNO5
Molar mass 275.0903 g mol−1
Pharmacology
A07AX02 (WHO) G01AB01 (WHO), P01CD02 (WHO), P51AD05 (WHO)
Hazards
GHS labelling:
GHS06: Toxic GHS09: Environmental hazard
Signal word
 Danger
H301, H331, H410
P261, P273, P301+P310, P311, P501
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N  (what is checkY☒N ?)
Infobox references

Acetarsol (or acetarsone[1]) is an anti-infective drug.[2]

It was first discovered in 1921 at Pasteur Institute by Ernest Fourneau,[3] and sold under the brand name Stovarsol.[4][5]

It has been given in the form of suppositories.[6]

Acetarsol can be used to make arsthinol.

References[]

  1. ^ "FDA Substance Registration System: Acetarsol". Retrieved 6 May 2021.
  2. ^ Chen MY, Smith NA, Fox EF, Bingham JS, Barlow D (April 1999). "Acetarsol pessaries in the treatment of metronidazole resistant Trichomonas vaginalis". Int J STD AIDS. 10 (4): 277–80. doi:10.1258/0956462991913943. PMID 12035784. S2CID 27353282.
  3. ^ PubChem. "Acetarsol". pubchem.ncbi.nlm.nih.gov. Retrieved 2021-03-31.
  4. ^ Éric Fouassier, Ces poisons qui guérissent, oct. 1996, p. 5.
  5. ^ Traité de chimie organique, sous la direction de Victor Grignard, Paul Baud, vol. 22, Masson, 1959, p. 1127-1130.
  6. ^ Gionchetti P, Rizzello F, Morselli C, Campieri M (October 2004). "Review article: problematic proctitis and distal colitis". Aliment. Pharmacol. Ther. 20 Suppl 4: 93–6. doi:10.1111/j.1365-2036.2004.02049.x. PMID 15352902. S2CID 72699260.
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