Cicortonide

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Cicortonide
Cicortonide.svg
Clinical data
Other names21-(Acetyloxy)-3-(2-chloroethoxy)-9α-fluoro-11β-hydroxy-16α,17α-[(1-methylethylidene)bis(oxy)]-20-oxopregna-3,5-diene-6-carbonitrile; 3-(2-Chloroethoxy)-9α-fluoro-11β,16α,17α,21-tetrahydroxy-20-oxopregna-3,5-diene-6-carbonitrile cyclic 16,17-acetal with acetone 21-acetate
Drug classCorticosteroid; Glucocorticoid
Identifiers
  • 2-[(4aS,4bR,5S,6aS,6bS,9aR,10aS,10bS)-2-(2-Chloroethoxy)-12-cyano-4b-fluoro-5-hydroxy-4a,6a,8,8-tetramethyl-3,4,4a,4b,5,6,6a,9a,10,10a,10b,11-dodecahydro-6bH-naphtho[2',1':4,5]indeno[1,2-d][1,3]dioxol-6b-yl]-2-oxoethyl acetate
CAS Number
PubChem CID
UNII
ChEMBL
Chemical and physical data
FormulaC29H37ClFNO7
Molar mass566.06 g·mol−1
3D model (JSmol)
  • CC(=O)OCC(=O)[C@@]12[C@@H](C[C@@H]3[C@@]1(C[C@@H]([C@]4([C@H]3CC(=C5[C@@]4(CCC(=C5)OCCCl)C)C#N)F)O)C)OC(O2)(C)C
  • InChI=1S/C29H37ClFNO7/c1-16(33)37-15-23(35)29-24(38-25(2,3)39-29)12-20-21-10-17(14-32)19-11-18(36-9-8-30)6-7-26(19,4)28(21,31)22(34)13-27(20,29)5/h11,20-22,24,34H,6-10,12-13,15H2,1-5H3/t20-,21-,22-,24+,26-,27-,28-,29+/m0/s1
  • Key:SOESEFMFRCCMQV-QWAPGEGQSA-N

Cicortonide is a synthetic glucocorticoid corticosteroid which was never marketed.[1]

References[]

  1. ^ Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 273–. ISBN 978-1-4757-2085-3.



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