Fluorometholone

Fluorometholone
Clinical data
Other names	(6S,8S,9R,10S,11S,13S,14S,17R)-17-acetyl-9-fluoro-11,17-dihydroxy-6,10,13-trimethyl-6,7,8,11,12,14,15,16-octahydrocyclopenta[a]phenanthren-3-one
AHFS/Drugs.com	Monograph
MedlinePlus	a682660
Pregnancy; category	C;
ATC code	C05AA06 (WHO) D07AB06 (WHO), D07XB04 (WHO) (combinations), D10AA01 (WHO), S01BA07 (WHO);
Identifiers
	show IUPAC name
CAS Number	426-13-1 ;
PubChem CID	9878;
IUPHAR/BPS	7079;
DrugBank	DB00324 ;
ChemSpider	9494 ;
UNII	SV0CSG527L;
KEGG	D01367 ;
ChEBI	CHEBI:31625 ;
ChEMBL	ChEMBL1200600 ;
CompTox Dashboard (EPA)	DTXSID7047435 ;
ECHA InfoCard	100.006.402
Chemical and physical data
Formula	C22H29FO4
Molar mass	376.468 g·mol−1
3D model (JSmol)	Interactive image;
	show SMILES
	show InChI
	(what is this?)

Fluorometholone (INN, BAN, JAN) (brand names Efflumidex, Flucon, FML Forte, FML, others), also known as 6α-methyl-9α-fluoro-11β,17α-dihydroxypregna-1,4-diene-3,20-dione, is a synthetic glucocorticoid which is used in the treatment of inflammatory eye diseases.^[1]^[2]^[3] The C17α acetate ester, fluorometholone acetate (brand name Flarex), is also a glucocorticoid and is used for similar indications.^[1]^[2]^[3] Specifically, it is indicated for use in the treatment of steroid-responsive inflammatory conditions of the palpebral and bulbar conjunctiva, cornea, and anterior segment of the eye.^{[citation needed]}

Most common indication for this drug is seasonal allergic conjunctivitis and other allergies of the eye.

References[]

^ Jump up to: ^a ^b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 566–. ISBN 978-1-4757-2085-3.
^ Jump up to: ^a ^b Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 458–. ISBN 978-3-88763-075-1.
^ Jump up to: ^a ^b Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 123–. ISBN 978-94-011-4439-1.

External links[]

Drugs.com
flarex
Alcon official page
Fluorometholone all you should know.

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[Elks2014-1] Jump up to: ^a ^b Elks J (14 November 2014). The Dictionary of Drugs: Chemical Data: Chemical Data, Structures and Bibliographies. Springer. pp. 566–. ISBN 978-1-4757-2085-3.

[IndexNominum2000-2] Jump up to: ^a ^b Index Nominum 2000: International Drug Directory. Taylor & Francis. January 2000. pp. 458–. ISBN 978-3-88763-075-1.

[MortonHall2012-3] Jump up to: ^a ^b Morton IK, Hall JM (6 December 2012). Concise Dictionary of Pharmacological Agents: Properties and Synonyms. Springer Science & Business Media. pp. 123–. ISBN 978-94-011-4439-1.

[1]

[2]

[3]

show v t Xenobiotic-sensing receptor modulators
CAR	Agonists: Amiodarone Artemisinin Carbamazepine Carvedilol Chlorpromazine Chrysin Clotrimazole Cyclophosphamide Cypermethrin DHEA (prasterone) Efavirenz Ellagic acid Griseofulvin Methoxychlor Mifepristone Nefazodone Nevirapine Nicardipine Permethrin Phenobarbital Phenytoin Pregnanedione (5β-dihydroprogesterone) Reserpine Telmisartan Tolnaftate Troglitazone Valproic acid Antagonists: 3α-Androstenol AITC Ethinylestradiol Meclizine Okadaic acid PK-11195
PXR	Agonists: 17α-Hydroxypregnenolone 17α-Hydroxyprogesterone Δ⁴-Androstenedione Δ⁵-Androstenediol Δ⁵-Androstenedione Allopregnanediol Allopregnanedione (5α-dihydroprogesterone) Allopregnanolone (brexanolone) Alpha-Lipoic acid Ambrisentan AMI-193 Amlodipine besylate Antimycotics Artemisinin Aurothioglucose Bile acids Bithionol Bosentan Cafestol Cephaloridine Cephradine Chlorpromazine Ciglitazone Clindamycin Clofenvinfos Chloroxine Clotrimazole Colforsin Corticosterone Cyclophosphamide Cyproterone acetate Demecolcine Dexamethasone DHEA (prasterone) DHEA-S (prasterone sulfate) Dibunate sodium Diclazuril Dicloxacillin Dimercaprol Docetaxel Docusate calcium Dodecylbenzenesulfonic acid Dronabinol Droxidopa Eburnamonine Ecopipam Enzacamene Epothilone B Erythromycin Famprofazone Felodipine Fenbendazole Fentanyl Flucloxacillin Fluorometholone Griseofulvin Guggulsterone Haloprogin Hetacillin potassium Hyperforin Hypericum perforatum (St John's wort) Indinavir sulfate Lasalocid sodium Levothyroxine Linolenic acid Loratadine Lovastatin Meclizine Metacycline Methylprednisolone Metyrapone Mevastatin Mifepristone Nafcillin Nicardipine Nicotine Nifedipine Nilvadipine Nisoldipine Norelgestromin Omeprazole Orlistat Oxatomide Paclitaxel Phenobarbital Piperine Plicamycin Prednisolone Pregnanediol Pregnanedione (5β-dihydroprogesterone) Pregnanolone Pregnenolone Pregnenolone 16α-carbonitrile Proadifen Progesterone Quingestrone Reserpine Reverse triiodothyronine Rifampicin Rifaximin Rimexolone Riodipine Ritonavir Simvastatin Sirolimus Spironolactone Spiroxatrine Sulfisoxazole Suramin Tacrolimus Terconazole Testosterone isocaproate Tetracycline Thiamylal sodium Thiothixene Thonzonium bromide Tianeptine Troglitazone Troleandomycin Zafirlukast Zeranol Antagonists: Ketoconazole Sesamin
See also Receptor/signaling modulators

Fluorometholone

See also[]

References[]

External links[]