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17α-Methyl-19-norprogesterone Other names H-3510; 17α-Methyl-19-norpregn-4-ene-3,20-dione; (17β)-17-Acetyl-17-methylestr-4-en-3-one Drug class Progestin ; Progestogen ChemSpider Formula C 21 H 30 O 2 Molar mass −1 3D model (JSmol )
O=C(C)[C@](C)1CC[C@]([H])2[C@@]([H])3CCC4=CC(CCC4C3CC[C@@]21C)=O
InChI=1S/C21H30O2/c1-13(22)20(2)11-9-19-18-6-4-14-12-15(23)5-7-16(14)17(18)8-10-21(19,20)3/h12,16-19H,4-11H2,1-3H3/t16-,17+,18+,19-,20+,21-/m0/s1
Key:SMHQTBXJLXZKNT-VXAANUECSA-N
17α-Methyl-19-norprogesterone (developmental code name H-3510 ), also known as 17α-methyl-19-norpregn-4-ene-3,20-dione , is a progestin which was never marketed.[1] [2] [3] derivative of progesterone , and is the combined derivative of 17α-methylprogesterone and 19-norprogesterone .[1] parent compound of a subgroup of the 19-norprogesterone group of progestins, which includes demegestone (the δ9 derivative), promegestone (the δ9 and 21-methyl derivative), and trimegestone (the δ9 , 21-methyl, and 21-hydroxyl derivative).[4]
See also [ ] References [ ]
^ a b Weiss, M.J.; Schaub, R.E.; Allen, G.R.; Poletto, J.F.; Pidacks, V.; Conrow, R.B.; Coscia, C.J. (1964). "The formation of steroid enolate anions by reductive procedures". Tetrahedron . 20 (2): 357–372. doi :10.1016/S0040-4020(01)93223-5 . ISSN 0040-4020 . ^ Raynaud JP, Philibert D, Azadian-Boulanger G (1974). "Progesterone-Progestin receptors". Basic Life Sci . 4 (PART A): 143–60. doi :10.1007/978-1-4684-2889-6_10 . ISBN 978-1-4684-2891-9 PMID 4374925 . ^ Delettré J, Mornon JP, Lepicard G, Ojasoo T, Raynaud JP (January 1980). "Steroid flexibility and receptor specificity". J. Steroid Biochem . 13 (1): 45–59. doi :10.1016/0022-4731(80)90112-0 . PMID 7382482 . ^ Kuhl H (2005). "Pharmacology of estrogens and progestogens: influence of different routes of administration". Climacteric . 8 Suppl 1: 3–63. doi :10.1080/13697130500148875 . PMID 16112947 . S2CID 24616324 .
PR
Agonists
Testosterone derivatives: Progestins: 6,6-Difluoronorethisterone 6,6-Difluoronorethisterone acetate 17α-Allyl-19-nortestosterone Allylestrenol Altrenogest Chloroethynylnorgestrel Cingestol Danazol Desogestrel Dienogest Ethinylandrostenediol
Ethisterone Ethynerone Etonogestrel Etynodiol Etynodiol diacetate Gestodene Gestrinone Levonorgestrel Levonorgestrel esters (e.g., levonorgestrel butanoate )Lynestrenol Lynestrenol phenylpropionate Metynodiol Metynodiol diacetate Norelgestromin Norethisterone (norethindrone) Norethisterone esters (e.g., norethisterone acetate , norethisterone enanthate )Noretynodrel Norgesterone Norgestimate Norgestrel Norgestrienone Norvinisterone Oxendolone Quingestanol Quingestanol acetate Tibolone Tigestol Tosagestin ; Anabolic–androgenic steroids: 11β-Methyl-19-nortestosterone 11β-Methyl-19-nortestosterone dodecylcarbonate 19-Nor-5-androstenediol 19-Nor-5-androstenedione 19-Nordehydroepiandrosterone Bolandiol Bolandiol dipropionate Bolandione Dimethisterone Dienedione Dienolone Dimethandrolone Dimethandrolone buciclate Dimethandrolone dodecylcarbonate Dimethandrolone undecanoate Dimethyldienolone Dimethyltrienolone Ethyldienolone Ethylestrenol (ethylnandrol) Methyldienolone Metribolone (R-1881) Methoxydienone (methoxygonadiene) Mibolerone Nandrolone Nandrolone esters (e.g., nandrolone decanoate , nandrolone phenylpropionate )Norethandrolone Normethandrone (methylestrenolone, normethandrolone, normethisterone) RU-2309 Tetrahydrogestrinone Trenbolone (trienolone) Trenbolone esters (e.g., trenbolone acetate , trenbolone enanthate )Trendione Trestolone Trestolone acetate MixedSPRMs Antagonists
mPR PAQR
See also
Receptor/signaling modulators Progestogens and antiprogestogens Androgen receptor modulators Estrogen receptor modulators List of progestogens
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