Circovirus

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Circovirus
Circovirus virion.jpg
Virus classification e
(unranked): Virus
Realm: Monodnaviria
Kingdom: Shotokuvirae
Phylum: Cressdnaviricota
Class: Arfiviricetes
Order: Cirlivirales
Family: Circoviridae
Genus: Circovirus

Circovirus is a genus of viruses, in the family Circoviridae. Birds (such as pigeons[1] and ducks[2]) and pigs[3] serve as natural hosts, though dogs have been shown to be infected as well.[4] It is a single stranded DNA virus (ssDNA). There are 49 species in this genus. Some members of this genus cause disease: PCV-1 is non pathogenic, while PCV-2 causes postweaning multisystemic wasting syndrome (PMWS).[5][6]

Taxonomy[]

The following species are recognized:

Structure[]

Viruses in Circovirus are non-enveloped, with icosahedral and round geometries, and T=1 symmetry. The diameter is around 17 nm. Genomes are circular and non-segmented.[5]

The virions of Circoviruses are surprisingly small, with diameters ranging from 17 up to 22 nm.[7]

Genus Structure Symmetry Capsid Genomic arrangement Genomic segmentation
Circovirus Icosahedral T=1 Non-enveloped Circular Monopartite

Life cycle[]

Viral replication is nuclear. Entry into the host cell is achieved by penetration. Replication follows the ssDNA rolling circle model. DNA templated transcription, with some alternative splicing mechanism is the method of transcription. The virus exits the host cell by nuclear egress, and nuclear pore export. Birds and pigs serve as the natural host. Transmission routes are fecal-oral and parental.[5]

Genus Host details Tissue tropism Entry details Release details Replication site Assembly site Transmission
Circovirus Birds; pigs None Cell receptor endocytosis Budding Nucleus Nucleus Horizontal; oral-fecal

References[]

  1. ^ Marlier, D; Vindevogel, H (July 2006). "Viral infections in pigeons". Veterinary Journal (London, England : 1997). 172 (1): 40–51. doi:10.1016/j.tvjl.2005.02.026. PMID 16772130.
  2. ^ Zhang, XX; Liu, SN; Xie, ZJ; Kong, YB; Jiang, SJ (June 2012). "Complete genome sequence analysis of duck circovirus strains from Cherry Valley duck". Virologica Sinica. 27 (3): 154–64. doi:10.1007/s12250-012-3214-4. PMC 8218041. PMID 22684469.
  3. ^ Chae, C (March 2012). "Porcine circovirus type 2 and its associated diseases in Korea". Virus Research. 164 (1–2): 107–13. doi:10.1016/j.virusres.2011.10.013. PMID 22027190.
  4. ^ Vogelsang, Jessica (September 14, 2013). "5 Things You Need to Know About the 'Circovirus Outbreak'". Yahoo News.
  5. ^ a b c "Viral Zone". ExPASy. Retrieved 15 June 2015.
  6. ^ "Virus Taxonomy: 2020 Release". International Committee on Taxonomy of Viruses (ICTV). March 2021. Retrieved 11 May 2021.
  7. ^ "Circovirus – microbewiki".

External links[]

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