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EA-2012
Names
Preferred IUPAC name
Bis(tetraphenylboranuide) N ,N ,N -trimethyl-3-({[(propan-2-yl)oxy](methylphosphonoyl)}oxy)-5-{4-[3-(trimethylazaniumyl)phenoxy]butoxy}anilinium
Identifiers
3D model (JSmol )
show
InChI=1S/C26H43N2O5P.2C24H20B/c1-21(2)32-34(9,29)33-26-19-23(28(6,7)8)18-25(20-26)31-16-11-10-15-30-24-14-12-13-22(17-24)27(3,4)5;2*1-5-13-21(14-6-1)25(22-15-7-2-8-16-22,23-17-9-3-10-18-23)24-19-11-4-12-20-24/h12-14,17-21H,10-11,15-16H2,1-9H3;2*1-20H/q+2;2*-1
Key: UBOLPSQXNCTHEF-UHFFFAOYSA-N
show
[B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.[B-](c1ccccc1)(c2ccccc2)(c3ccccc3)c4ccccc4.CC(C)OP(=O)(C)Oc5cc([N+](C)(C)C)cc(c5)OCCCCOc6cccc(c6)[N+](C)(C)C
Properties
Chemical formula
C 74 H 83 B 2 N 2 O 5 P
Molar mass
1133 .08 g·mol−1
Appearance
Solid
Melting point
171–172 °C (340–342 °F; 444–445 K)
Insoluble
Solubility
Soluble in acetone
Hazards
Main hazards
Extremely toxic
Lethal dose or concentration (LD, LC):
LD50 (median dose )
93 μg/kg (Rats, IV) 17 μg/kg (Rabbits, IV)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
Infobox references
Chemical compound
EA-2012 is an extremely toxic organophosphate nerve agent . It's an extremely potent acetylcholinesterase inhibitor that is resistant to atropine and oxime treatment.[1]
See also [ ]
Nerve agent
EA-2054
EA-2098
EA-2613
References [ ]
show Agents used in chemical warfare incapacitation riot control Blood agents
Cyanogen [citation needed ]
Cyanogen bromide
Cyanogen chloride (CK)
Hydrogen cyanide (AC)
Arsine
Hydrogen sulfide
Phosphine
Carbon monoxide
Phosphorus trifluoride
Methyl cyanoformate
Blister agents
Arsenicals
Ethyldichloroarsine (ED)
Methyldichloroarsine (MD)
Phenyldichloroarsine (PD)
Lewisite (L)
Mustard gas (HD H HT HL HQ)
Nitrogen mustard
Nerve agents
Neurotoxins
Saxitoxin (TZ)
Botulinum toxin (BTX)
Tetanospasmin (TeNT)
Chlorophenylsilatrane
Tetrodotoxin
Aconitine
Tetraethyllead
Nettle agents Pulmonary/ choking agents Vomiting agents Incapacitating agents
Agent 15 (BZ)
Dimethylheptylpyran (DMHP)
EA-3167
EA-3443
EA-3580
EA-3834
Kolokol-1
LSD-25
PAVA spray
Sleeping gas
Lachrymatory agents
Xylyl bromide
Pepper spray (OC)
Mace (spray)
CN
CS
CR
CNS
Benzyl chloride
Benzyl bromide
Benzyl iodide
Bromobenzyl cyanide
Thiophosgene
Chloroacetone
Bromoacetone
Acrolein
Phenacyl bromide
Chloroacetophenone oxime
Ethyl bromoacetate
Ethyl iodoacetate
Other
Methyl fluoroacetate
Fluoroethyl fluoroacetate
Ricin
Abrin
Enterotoxin type B
Depleted uranium
White phosphorus
List of chemical warfare agents
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Bacterial
Botulinum toxin
Tetanospasmin
Cyanotoxins Plant toxins Mycotoxins Pesticides Nerve agents
Cyclosarin
EA-3148
Novichok agent
Sarin
Soman
Tabun
VE
VG
VM
VP
VR
VX
GV
EA-3990
EA-4056
T-1123
Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)
Fluorotabun
Chinese VX
EA-2192
Bicyclic phosphates Other
show Enzyme (modulators )
Transporter (modulators )
Release (modulators )
Inhibitors
SNAP-25 inactivators: Botulinum toxin (A , , )
VAMP inactivators: Botulinum toxin (, , , )
Enhancers
LPHN agonists: α-Latrotoxin
Others: Atracotoxins (e.g., robustoxin , )
Crotoxin
See also: Receptor/signaling modulators • Muscarinic acetylcholine receptor modulators • Nicotinic acetylcholine receptor modulators
Categories :
Organophosphate nerve agents Acetylcholinesterase inhibitors Quaternary ammonium compounds Phenol ethers Phenol esters Phosphonate esters Isopropyl esters Tetraphenylborates Ester stubs Hidden categories:
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