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EA-2192
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Names
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Preferred IUPAC name
S-{2-[Di(propan-2-yl)amino]ethyl} methylphosphonothioate
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Other names
Diisopropylaminoethyl methyl thiolophosphonate
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Identifiers
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3D model (JSmol)
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ChemSpider
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show
CC(C)N(CCSP(=O)(C)O)C(C)C
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Properties
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Chemical formula
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C9H22NO2PS
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Molar mass
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239.31 g·mol−1
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Appearance
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White solid
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Very soluble
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Hazards
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Main hazards
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Extremely toxic
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Lethal dose or concentration (LD, LC):
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LD50 (median dose)
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630 μg/kg (Rat, oral) 18 μg/kg (Rat, iv) 50 μg/kg (Mouse, iv)
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Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
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Infobox references
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Chemical compound
EA-2192 is an extremely toxic degradation product of the VX nerve agent.[1][2] It is a white solid that is very soluble and stable in water.
EA-2192 is an extremely potent acetylcholinesterase inhibitor. It is almost as toxic as VX itself.[3]
See also[]
- Nerve agent
- VX (nerve agent)
References[]
- ^ Ellison, D. Hank (2007). Handbook of chemical and biological warfare agents (2nd ed.). Boca Raton, Fla.: CRC. ISBN 9780849314346.
- ^ Hoenig, Steven L. (2007), Compendium of Chemical Warfare Agents, Springer, ISBN 978-0-387-34626-7
- ^ Munro, NB; Talmage, SS; Griffin, GD; Waters, LC; Watson, AP; King, JF; Hauschild, V (December 1999). "The sources, fate, and toxicity of chemical warfare agent degradation products". Environmental Health Perspectives. 107 (12): 933–74. doi:10.1289/ehp.99107933. PMC 1566810. PMID 10585900.
show- Agents used in chemical warfare
- incapacitation
- riot control
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Blood agents |
- Cyanogen[citation needed]
- Cyanogen bromide
- Cyanogen chloride (CK)
- Hydrogen cyanide (AC)
- Arsine
- Hydrogen sulfide
- Phosphine
- Carbon monoxide
- Phosphorus trifluoride
- Methyl cyanoformate
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Blister agents |
- Arsenicals
- Ethyldichloroarsine (ED)
- Methyldichloroarsine (MD)
- Phenyldichloroarsine (PD)
- Lewisite (L)
- Mustard gas (HD H HT HL HQ)
- Nitrogen mustard
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Nerve agents | |
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Neurotoxins |
- Saxitoxin (TZ)
- Botulinum toxin (BTX)
- Tetanospasmin (TeNT)
- Chlorophenylsilatrane
- Tetrodotoxin
- Aconitine
- Tetraethyllead
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Nettle agents | |
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Pulmonary/ choking agents | |
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Vomiting agents | |
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Incapacitating agents |
- Agent 15 (BZ)
- Dimethylheptylpyran (DMHP)
- EA-3167
- EA-3443
- EA-3580
- EA-3834
- Kolokol-1
- LSD-25
- PAVA spray
- Sleeping gas
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Lachrymatory agents |
- Xylyl bromide
- Pepper spray (OC)
- Mace (spray)
- CN
- CS
- CR
- CNS
- Benzyl chloride
- Benzyl bromide
- Benzyl iodide
- Bromobenzyl cyanide
- Thiophosgene
- Chloroacetone
- Bromoacetone
- Acrolein
- Phenacyl bromide
- Chloroacetophenone oxime
- Ethyl bromoacetate
- Ethyl iodoacetate
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Other |
- Methyl fluoroacetate
- Fluoroethyl fluoroacetate
- Ricin
- Abrin
- Enterotoxin type B
- Depleted uranium
- White phosphorus
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- List of chemical warfare agents
- CB military symbol
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show Neurotoxins |
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Bacterial |
- Botulinum toxin
- Tetanospasmin
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Cyanotoxins | |
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Plant toxins | |
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Mycotoxins | |
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Pesticides | |
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Nerve agents |
- Cyclosarin
- EA-3148
- Novichok agent
- Sarin
- Soman
- Tabun
- VE
- VG
- VM
- VP
- VR
- VX
- GV
- EA-3990
- EA-4056
- T-1123
- Octamethylene-bis(5-dimethylcarbamoxyisoquinolinium bromide)
- Fluorotabun
- Chinese VX
- EA-2192
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Bicyclic phosphates | |
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Other | |
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show |
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Enzyme (modulators) | |
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Transporter (modulators) | |
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Release (modulators) | Inhibitors |
- SNAP-25 inactivators: Botulinum toxin (A, , )
- VAMP inactivators: Botulinum toxin (, , , )
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Enhancers |
- LPHN agonists: α-Latrotoxin
- Others: Atracotoxins (e.g., robustoxin, )
- Crotoxin
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See also: Receptor/signaling modulators • Muscarinic acetylcholine receptor modulators • Nicotinic acetylcholine receptor modulators |
Categories:
- V-series nerve agents
- Phosphonothioates
- Phosphonic acids
- Acetylcholinesterase inhibitors
- Diisopropylamino compounds
- Organic compound stubs
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